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Changes in maternal age and prevalence of congenital anomalies during the enactment of China's universal two-child policy (2013-2017) in Zhejiang Province, China: An observational study

期刊: PLOS MEDICINE, 2020; 17 (2)

Background China implemented a partial two-child policy (2013) followed by a universal two-child policy (2015), replacing the former one-child policy ......

Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study

期刊: PLOS MEDICINE, 2020; 17 (2)

Background There is very limited data on the time trend of diabetes incidence in Asia. Using population-level data, we report the secular trend of the......

Spatiotemporal trends and ecological determinants in maternal mortality ratios in 2,205 Chinese counties, 2010-2013: A Bayesian modelling analysis

期刊: PLOS MEDICINE, 2020; 17 (5)

Background As one of its Millennium Development Goals (MDGs), China has achieved a dramatic reduction in the maternal mortality ratio (MMR), although ......

Multimorbidity, mortality, and HbA1c in type 2 diabetes: A cohort study with UK and Taiwanese cohorts

期刊: PLOS MEDICINE, 2020; 17 (5)

Background There is emerging interest in multimorbidity in type 2 diabetes (T2D), which can be either concordant (T2D related) or discordant (unrelate......

Clinical and epidemiological characteristics of pediatric SARS-CoV-2 infections in China: A multicenter case series

期刊: PLOS MEDICINE, 2020; 17 (6)

Background As of April 18, 2020, over 2,000,000 patients had been diagnosed with coronavirus disease-2019 (COVID-19) globally, and more than 140,000 d......

Can self-imposed prevention measures mitigate the COVID-19 epidemic?

期刊: PLOS MEDICINE, 2020; 17 (7)

Yuming Guo and colleagues discuss the research by Teslya et al that highlights the importance of personal preventative measures in avoiding a second w......

Temporal trends of the association between ambient temperature and hospitalisations for cardiovascular diseases in Queensland, Australia from 1995 to 2016: A time-stratified case-crossover study

期刊: PLOS MEDICINE, 2020; 17 (7)

Background In the context of global warming, studies have turned to assess the temporal trend of the association between temperature and health outcom......

Detection rate and treatment gap for atrial fibrillation identified through screening in community health centers in China (AF-CATCH): A prospective multicenter study

期刊: PLOS MEDICINE, 2020; 17 (7)

Author summaryWhy was this study done? Atrial fibrillation (AF) is a common heart rhythm problem that often has no symptoms, so it is often underdiagn......

Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China

期刊: PLOS MEDICINE, 2020; 17 (7)

Background As of June 1, 2020, coronavirus disease 2019 (COVID-19) has caused more than 6,000,000 infected persons and 360,000 deaths globally. Previo......

Obesity, clinical, and genetic predictors for glycemic progression in Chinese patients with type 2 diabetes: A cohort study using the Hong Kong Diabetes Register and Hong Kong Diabetes Biobank

期刊: PLOS MEDICINE, 2020; 17 (7)

Author summaryWhy was this study done? There is marked heterogeneity in the rate of progression to insulin requirement in patients with type 2 diabete......

The global burden of disease attributable to high body mass index in 195 countries and territories, 1990-2017: An analysis of the Global Burden of Disease Study

期刊: PLOS MEDICINE, 2020; 17 (7)

Background Obesity represents an urgent problem that needs to be properly addressed, especially among children. Public and global health policy- and d......

Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

期刊: PLOS MEDICINE, 2020; 17 (5)

Background The radical cure of Plasmodium vivax and P. ovale requires treatment with primaquine or tafenoquine to clear dormant liver stages. Either d......

Associations among circulating sphingolipids, beta-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China

期刊: PLOS MEDICINE, 2020; 17 (12)

Author summary Why was this study done? Ceramides are members of the sphingolipid family that have been reported to be pathophysiologically relevant f......

The association between long-term exposure to low-level PM(2.5)and mortality in the state of Queensland, Australia: A modelling study with the difference-in-differences approach

期刊: PLOS MEDICINE, 2020; 17 (6)

Background To date, few studies have investigated the causal relationship between mortality and long-term exposure to a low level of fine particulate ......

Studying individual risk factors for self-harm in the UK Biobank: A polygenic scoring and Mendelian randomisation study

期刊: PLOS MEDICINE, 2020; 17 (6)

Background Identifying causal risk factors for self-harm is essential to inform preventive interventions. Epidemiological studies have identified risk......

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