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Epigenetic mechanism of L-type calcium channel beta-subunit downregulation in short QT human induced pluripotent stem cell-derived cardiomyocytes with CACNB2 mutation

期刊: EUROPACE, 2022; 24 (12)

Aims A loss-of-function mutation in L-type calcium (Ca2+) channel subunit gene CACNB2 has been reported to cause short QT syndrome subtype 5 (SQT5). H......

JIF:3.246

Association between sodium-glucose cotransporter-2 inhibitors and risk of sudden cardiac death or ventricular arrhythmias: a meta-analysis of randomized controlled trials

期刊: EUROPACE, 2022; 24 (1)

Aims Sudden cardiac death (SCD) and ventricular arrhythmias (VAs) are important causes of mortality in patients with type 2 diabetes mellitus (T2DM), ......

JIF:3.246

Preclinical short QT syndrome models: studying the phenotype and drug-screening

期刊: EUROPACE, 2022; 24 (3)

Cardiovascular diseases are the main cause of sudden cardiac death (SCD) in developed and developing countries. Inherited cardiac channelopathies are ......

JIF:3.246

Digoxin use and clinical outcomes in elderly Chinese patients with atrial fibrillation: a report from the Optimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) registry

期刊: EUROPACE, 2022; 24 (7)

Aims Prior studies have reported conflicting results on digoxin's impact on clinical outcomes and quality of life, and there are limited data from Asi......

JIF:3.246

MFAP4 deletion attenuates the progression of angiotensin II-induced atrial fibrosis and atrial fibrillation

期刊: EUROPACE, 2022; 24 (2)

Aims Microfibrillar-associated protein 4 (MFAP4) is associated with atrial fibrillation (AF). Nevertheless, the specific role and underlying mechanism......

JIF:3.246

Effects of intensive blood pressure control on cardiovascular and cognitive outcomes in patients with atrial fibrillation: insights from the SPRINT trial

期刊: EUROPACE, 2022; 24 (10)

Aims Patients with atrial fibrillation (AF) have an increased risk of cardiovascular events and dementia, even if anticoagulated. Hypertension is high......

JIF:3.246

Risk of incident atrial fibrillation with low-to-moderate alcohol consumption is associated with gender, region, alcohol category: a systematic review and meta-analysis

期刊: EUROPACE, 2022; 24 (5)

Aims The association between low-to-moderate alcohol consumption and atrial fibrillation (AF) has yet to be fully elucidated. The main purpose of this......

JIF:3.246

Non-vitamin K oral anticoagulants and risk of fractures: a systematic review and meta-analysis

期刊: EUROPACE, 2021; 23 (1)

Aims Comparative fracture risk for non-vitamin K antagonist oral anticoagulants (NOACs) and vitamin K antagonists (VKAs) among patients with atrial fi......

Comparative data on left atrial appendage occlusion efficacy and clinical outcomes by age group in theAmplatzer (TM) Amulet (TM) Occluder Observational Study

期刊: EUROPACE, 2021; 23 (2)

Aims Left atrial appendage occlusion (LAAO) may be considered for patients with non-valvular atrial fibrillation (NVAF) and a relative/formal contrain......

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