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Circ_0057583 facilitates brain microvascular endothelial cell injury through modulating miR-204-5p/NR4A1 axis

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (2)

Lipopolysaccharide (LPS) can induce vascular endothelial injury. Circular RNAs (circRNAs) have been verified to regulate different cellular processes ......

JIF:3.228

Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (5)

Vascular dementia (VaD) is the second cause of dementia after Alzheimer's disease. Ligustilide (LIG) is one of the main active ingredients of traditio......

JIF:3.228

LncRNA ZFAS1 regulates the hippocampal neurons injury in epilepsy through the miR-15a-5p/OXSR1/NF-kappa B pathway

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (7)

Long non-coding RNAs (lncRNAs) have been confirmed to be involved in epilepsy development. It has been reported that lncRNA ZFAS1 plays a vital regula......

JIF:3.228

Remote ischemic preconditioning protects against cerebral ischemia injury in rats by upregulating miR-204-5p and activating the PINK1/Parkin signaling pathway

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (4)

Remote ischemic preconditioning (RiPC) is the process where preconditioning ischemia protects the organs against the subsequent index ischemia. RiPC i......

JIF:3.228

Alzheimer's disease therapy based on acetylcholinesterase inhibitor/blocker effects on voltage-gated potassium channels

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (3)

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder with progressive loss of memory and other cognitive functions. The pathogene......

JIF:3.228

MiR-487b suppressed inflammation and neuronal apoptosis in spinal cord injury by targeted Ifitm3

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (7)

Spinal cord injury (SCI) was a serious nerve injury, which involves complex genetic changes. This paper was intended to investigate the function and m......

JIF:3.228

Tetramethylpyrazine protects neural stem cells against sevoflurane-induced toxicity through Akt/GSK-3 beta pathway

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (7)

Sevoflurane, a commonly used anesthetic, has been found to cause neural stem cell (NSC) injury, thereby contributing to neurocognitive impairment foll......

JIF:3.228

Heterotopic 4T1 breast cancer transplantation induces hippocampal inflammation and depressive-like behaviors in mice

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (8)

Cancer and its accompanying treatments can lead to numerous physical and emotional concerns, including subclinical or clinical depression and anxiety,......

JIF:3.228

Circ_0003611 regulates apoptosis and oxidative stress injury of Alzheimer's disease via miR-383-5p/KIF1B axis

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (8)

Alzheimer's disease (AD) is a high incidence neurodegenerative disease. Emerging evidence suggests that circular RNAs (circRNAs) play an important mod......

JIF:3.228

Phoenixin-20 ameliorates brain infarction by promoting microglia M2 polarization in an ischemic stroke model

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (5)

Ischemic stroke is one of the most common causes of death worldwide. The transformation of microglia from the classic M1 to the alternative M2 state h......

JIF:3.228

SAM, a cystathionine beta-synthase activator, promotes hydrogen sulfide to promote neural repair resulting from massive cerebral infarction induced by middle cerebral artery occlusion

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (5)

Neurologic deterioration after massive cerebral infarct should be identified at an early stage for medical and surgical treatments. We investigated th......

JIF:3.228

RXR gamma attenuates cerebral ischemia-reperfusion induced ferroptosis in neurons in mice through transcriptionally promoting the expression of GPX4

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (5)

Cerebral ischemia is a common cerebrovascular disease with high mortality and disability rate. Exploring its mechanism is essential for developing eff......

JIF:3.228

Identification of methylation markers for diagnosis of autism spectrum disorder

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (1)

Autism spectrum disorder (ASD) is a hereditary heterogeneous neurodevelopmental disorder characterized by social and speech dysplasia. We collected th......

JIF:3.228

METTL7B contributes to the malignant progression of glioblastoma by inhibiting EGR1 expression

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (4)

Glioblastoma (GBM), a predominant central nervous system (CNS) malignancy, is correlated with high mortality and severe morbidity. Mammalian methyltra......

JIF:3.228

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