期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (5)
The gut microbiota plays an important role in regulating the pharmacokinetics and pharmacodynamics of many drugs. FLZ, a novel squamosamide derivative......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (7)
Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity when chelated with copper (Cu). However, the low ......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (6)
Anoctamin 1 (ANO1) or TMEM16A gene encodes a member of Ca2+ activated Cl- channels (CaCCs) that are critical for physiological functions, such as epit......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (7)
Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. How......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (7)
Hepatocellular carcinoma (HCC) has been known as the second common leading cancer worldwide, as it responds poorly to both chemotherapy and medication......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (4)
As one of the most important components of caveolae, caveolin-1 is involved in caveolae-mediated endocytosis and transcytosis pathways, and also plays......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (4)
In this study, self-discriminating hybrid nanocrystals was utilized to explore the biological fate of quercetin hybrid nanocrystals (QT-HNCs) with dia......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (5)
Therapeutic nanoparticles are designed to enhance efficacy, real-time monitoring, targeting accuracy, biocompatibility, biodegradability, safety, and ......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (7)
Rheumatoid arthritis (RA) is an autoimmune disease and is mainly characterized by abnormal proliferation of fibroblast-like synoviocytes (FLS). The up......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (8)
Pharmaceutical cocrystals are multicomponent systems in which at least one component is an active pharmaceutical ingredient and the others are pharmac......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (4)
The initiation and development of major inflammatory diseases, i.e., cancer, vascular inflammation, and some autoimmune diseases are closely linked to......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (7)
Anoctamin 1 (ANO1) is a kind of calcium-activated chloride channel involved in nerve depolarization. ANO1 inhibitors display significant analgesic act......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (8)
Three-dimensional printing is a technology that prints the products layer-by-layer, in which materials are deposited according to the digital model de......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (2)
Developing tumor-specific drug delivery systems with minimized off-target cargo leakage remains an enduring challenge. In this study, inspired from th......
期刊： ACTA PHARMACEUTICA SINICA B, 2021; 11 (4)
Self-microemulsifying drug delivery systems (SMEDDSs) have recently returned to the lime-light of academia and industry due to their enormous potentia......
