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Ethnic differences in 25-year risk of incident chronic kidney disease among people with type 2 diabetes in New Zealand

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (6)

IntroductionInsights into ethnic differences in the natural history of chronic kidney disease (CKD) among people with type 2 diabetes mellitus (T2DM) ......

Advanced glycation end products correlate with breast cancer metastasis by activating RAGE/TLR4 signaling

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (2)

Introduction This study was aimed to investigate the mechanisms of advanced glycation end products (AGEs) in promoting invasion and metastasis of brea......

Better TIR, HbA1c, and less hypoglycemia in closed-loop insulin system in patients with type 1 diabetes: a meta-analysis

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (2)

The study aimed to evaluate the effectiveness and safety of long-term use of closed-loop insulin system (CLS) in non-pregnant patients with type 1 dia......

Network Mendelian randomization study: exploring the causal pathway from insomnia to type 2 diabetes

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (1)

Introduction Insomnia is a novel pathogen for type 2 diabetes mellitus (T2DM). However, mechanisms linking insomnia and T2DM are poorly understood. In......

Serum isthmin-1 levels are positively and independently correlated with albuminuria in patients with type 2 diabetes mellitus

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (5)

Introduction Isthmin-1 (Ism-1), as a novel adipokine, plays a role in glucose homeostasis and lipid metabolism. However, the relationship between Ism-......

Digital solution for detection of undiagnosed diabetes using machine learning-based retinal image analysis

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (6)

IntroductionUndiagnosed diabetes is a global health issue. Previous studies have estimated that about 24.1%-75.1% of all diabetes cases are undiagnose......

First trimester plasma microRNAs levels predict Matsuda Index-estimated insulin sensitivity between 24th and 29th week of pregnancy

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (2)

Introduction Gestational diabetes mellitus (GDM) is a consequence of an imbalance between insulin sensitivity (IS) and secretion during pregnancy. Mic......

CD36 inhibition partially attenuates myocardial injury in diabetic rats with ischemic postconditioning

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (5)

Introduction To investigate the role of CD36 (fatty acid translocation enzyme) in the myocardial ischemia reperfusion (IR) injury in diabetes with isc......

Plasma C1q/tumor necrosis factor-related protein-3 concentrations are associated with diabetic peripheral neuropathy

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (2)

Introduction To analyze the associations of circulating C1g/tumor necrosis factor-related protein-3 (CTRP3) concentrations with several metabolic para......

Insulin resistance based on postglucose load measure is associated with prevalence and burden of cerebral small vessel disease

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (5)

Introduction Cerebral small vessel disease (cSVD) is highly prevalent and results in irreversible cognitive impairment and reduced quality of life. Pr......

Alterations in plantar vessel blood flow in patients with mild diabetic peripheral neuropathy

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (1)

Introduction Early identification and treatment of diabetic peripheral neuropathy (DPN) are crucial. Presently, the mechanism of DPN is not very clear......

Temporal sequence of blood lipids and insulin resistance in perimenopausal women: the study of women's health across the nation

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (2)

Introduction To explore the temporal relationship between blood lipids and insulin resistance in perimenopausal women. Research design and methods The......

Effects of resistance exercise on blood glucose level and pregnancy outcome in patients with gestational diabetes mellitus: a randomized controlled trial

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (2)

Introduction To date, the effects of resistance exercise on diabetes-related parameters (blood glucose level and insulin use) and pregnancy outcome in......

Prevalence of long-term complications in inpatients with diabetes mellitus in China: a nationwide tertiary hospital-based study

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (3)

Introduction There is absence of national data to estimate the prevalence of long-term diabetic complications among inpatients with diabetes in tertia......

Metformin modulates the gut microbiome in a mice model of high-fat diet-induced glycolipid metabolism disorder

期刊: BMJ OPEN DIABETES RESEARCH & CARE, 2022; 10 (6)

IntroductionMetformin (MET) can regulate glucose and lipid levels, and the gut microbiota may be involved in the control of metabolism. We hypothesize......

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