期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 153 (4)
Although microglia are associated with chronic pain, the role of spinal microglia in the regulation of itch remains unclear. In this study, we charact......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 151 (2)
Caffeic acid has been indicated to benefit cholesterol balance, but the effect of pure caffeic acid on atherosclerosis in vivo has not been tested. Gi......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 151 (4)
Histamine is a well-known inflammatory mediator, but how histamine induces angiogenesis remains poorly understood. In the present study, we demonstrat......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 152 (1)
Purpose: Oral administration of 5-aminolevulinic acid hydrochloride (5-ALA-HCl) has been reported to enhance the hypotensive effects associated with a......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 152 (2)
We investigated the extracellular Ca2+ influx pathways involved in platelet-activating factor (PAF)enhanced guinea pig detrusor smooth muscle (DSM) co......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 153 (3)
Transporter-mediated clearance is determined by two factors, its single-molecule clearance, and expression level. However, no reliable method has been......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 151 (2)
Mirtazapine, an atypical antidepressant, is known to enhance serotonergic transmission by inhibiting the 5-hydroxytryptamine (5-HT)1A, 5-HT2C, and 5-H......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 151 (2)
Pulmonary arterial hypertension (PAH) is a progressive and fatal disease that is characterized by vascular remodeling of the pulmonary artery. PAH rem......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 153 (3)
Increasing evidence indicates that immune abnormalities are associated with the pathogenesis of depression. CCR4 is a chemokine receptor that regulate......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 151 (1)
Atherosclerotic plaques develop from the accumulation of macrophage-derived foam cells via the uptake of modified low-density lipoprotein (LDL). CD36 ......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 153 (3)
The usefulness of NUDT15 genotyping as a pharmacogenomic test for thiopurine has been established. The first such test developed to date, NUDT15 genot......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 151 (1)
Triamcinolone acetonide (TA) has been shown to improve morphological and functional outcome in diabetic macular edema (DME) patients. However, the fun......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 153 (1)
SET and MYND domain protein 2 (SMYD2) can methylate histone H3 at lysine36 (H3K36) and some non -histone substrates to play a role in tumorigenesis. H......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 151 (4)
Allyl isothiocyanate (AITC) activates transient receptor potential ankyrin 1 (TRPA1) channel, which is involved in the control of intestinal mucosal b......
期刊： JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023; 152 (1)
Fatigue is a serious health problem, and long-term fatigue can lead to mental illnesses and accelerated aging. Oxidative stress, which causes excessiv......
