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Investigation of virulence factors in Pseudomonas aeruginosa isolates by phenotypic and genotypic methods

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; ()

Introduction: Pseudomonas aeruginosa possesses a variety of virulence factors that may contribute to its pathogenicity, and relationship has been dete......

Properties of artificial cationic oligodiaminosaccharides and oligopeptides that bind to A-type oligonucleotide duplexes

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (8)

A critical strategy to improve the properties of oligonucleotide therapeutics is using cationic molecules as carriers. We developed artificial cationi......

Solvolysis of 2'-deoxyribonucleosides and oligo-2'-deoxyribonucleotides in aqueous pyrrolidine or ammonia solutions

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (10)

To assess the feasibility of high-temperature aminolysis of deoxyribooligonucleotides containing rare bases as a method to determine their base sequen......

IL2RA rs2104286 and IL2 rs2069762 polymorphisms may be associated with bipolar disorder and its clinical findings

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; ()

Study results supported that immuno-inflammatory pathways in the brain and environment contribute to the etiopathogenesis of bipolar disorder (BD), a ......

Alterations in the expression levels of long intergenic non-coding RNA APOC1P1-3 in cervical cancer tissue samples

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (6)

lncRNAs play a crucial role in the carcinogenesis process. Thus, they have been recognized as the potential therapeutic and diagnostic biomarkers of c......

Association between TLR2, TLR4, and TLR5 genetic variants and the risk of hepatocellular carcinoma in Moroccan population

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (12)

Hepatocellular carcinoma (HCC) is the fifth most common human malignancy and the fourth most frequent cause of cancer-related deaths worldwide. Toll-l......

Lack of association between VNTR variant of the circadian gene (PER3) and major depressive disorder in a sample of a Turkish population

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; ()

Major depressive disorder (MDD), which is a prevalent psychiatric disorder, is characterized by sleep-wake disturbances. An underlying circadian rhyth......

Insights on the nuclear shuttling of H2A-H2B histone chaperones

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; ()

All cellular processes that involve the unwinding of DNA also lead to the systematic shuttling of histones. Histone shuttling across the nuclear membr......

The effects of taurine supplementation on obesity and browning of white adipose tissue in high-fat diet-fed mice

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (2)

Background: In recent years, a new type of adipose tissue (beige adipose tissue) has been mentioned, unlike white adipose tissue (WAT) and brown adipo......

Role of VEGF I/D variant in suspectibility to odontogenic cyst formation

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (4)

Odontogenic cysts, are located in the jawbones, filled with fluid surrounded by epithelial lining and fibrous connective tissue. Vascular endothelial ......

Identification of the effects of pathogenic genetic variations of human CYP2C9 and CYP2D6: an in silico approach

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; ()

Genetic variations in the human cytochrome P450 family 2 subfamily C member 9 (CYP2C9) and cytochrome P450 family 2 subfamily D member 6 (CYP2D6) gene......

Investigation of circadian rhythm gene Per3 in diabetic neuropathy

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; ()

Purpose: Diabetic neuropathy (DN) is a serious complication of diabetes that affects peripheral and autonomic nerves, and it has been linked to irregu......

TERT silencing alters the expression of ARG1, GLUL, VIM, NES genes and hsa-miR-29b-3p in the T98G cell line

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (6)

The central function of telomerase is maintaining the telomere length. However, several extra-telomeric roles have been identified for this protein co......

Alkylation of 6-thiopurine derivatives by the Mitsunobu reaction

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (7)

Alkylation of thiopurine derivatives with alcohols by the Mitsunobu reaction are reported in moderated to good yields. The method was applied in synth......

The investigation of host genetic variants of toll-like receptor 7 and 8 in COVID-19

期刊: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2023; 42 (8)

Toll-like receptors (TLRs) recognize infectious agents and play an important role in the innate immune system. Studies have suggested that TLR single ......

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