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Gut microbiota mediate melatonin signalling in association with type 2 diabetes

期刊: DIABETOLOGIA, 2022; 65 (10)

Aims/hypothesis It has been shown that melatonin plays a general beneficial role in type 2 diabetes in rodents but its role in humans is controversial......

JIF:8.049

Familial aggregation and shared genetic loading for major psychiatric disorders and type 2 diabetes

期刊: DIABETOLOGIA, 2022; 65 (5)

Aims/hypothesis Psychiatric disorders, such as schizophrenia (SCZ), major depressive disorder (MDD) and bipolar disorder (BPD), are highly comorbid wi......

JIF:8.049

Using genetics to assess the association of commonly used antihypertensive drugs with diabetes, glycaemic traits and lipids: a trans-ancestry Mendelian randomisation study

期刊: DIABETOLOGIA, 2022; 65 (4)

Aims/hypothesis Diabetes and hyperlipidaemia are common comorbidities in people with hypertension. Despite similar protective effects on CVD, differen......

JIF:8.049

Associations of plasma glycerophospholipid profile with modifiable lifestyles and incident diabetes in middle-aged and older Chinese

期刊: DIABETOLOGIA, 2022; 65 (2)

Aims/hypothesis Glycerophospholipid (GPL) perturbance was linked to the pathogenesis of diabetes in animal studies but prospective studies in humans a......

JIF:8.049

Relative leucocyte telomere length is associated with incident end-stage kidney disease and rapid decline of kidney function in type 2 diabetes: analysis from the Hong Kong Diabetes Register

期刊: DIABETOLOGIA, 2022; 65 (2)

Aims/hypothesis Few large-scale prospective studies have investigated associations between relative leucocyte telomere length (rLTL) and kidney dysfun......

JIF:8.049

Associations of polysocial risk score, lifestyle and genetic factors with incident type 2 diabetes: a prospective cohort study

期刊: DIABETOLOGIA, 2022; 65 (12)

Aim/hypothesis We aimed to investigate the association between polysocial risk scow (PsRS), an estimator of individual-level exposure to cumulative so......

JIF:8.049

MicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway

期刊: DIABETOLOGIA, 2022; 65 (3)

Aims/hypothesis Type 2 diabetes is associated with a reduction in skeletal muscle mass; however, how the progression of sarcopenia is induced and regu......

JIF:8.049

The efficacy of canagliflozin in diabetes subgroups stratified by data-driven clustering or a supervised machine learning method: a post hoc analysis of canagliflozin clinical trial data

期刊: DIABETOLOGIA, 2022; 65 (9)

Aims/hypothesis Data-driven diabetes subgroups have shown distinct clinical characteristics and disease progression, although there is a lack of evide......

JIF:8.049

Association of gut microbiota with glycaemic traits and incident type 2 diabetes, and modulation by habitual diet: a population-based longitudinal cohort study in Chinese adults

期刊: DIABETOLOGIA, 2022; 65 (7)

Aims/hypothesis The gut microbiome is mainly shaped by diet, and varies across geographical regions. Little is known about the longitudinal associatio......

JIF:8.049

Evaluating the efficacy and mechanism of metformin targets on reducing Alzheimer's disease risk in the general population: a Mendelian randomisation study

期刊: DIABETOLOGIA, 2022; 65 (10)

Aims/hypothesis Metformin use has been associated with reduced incidence of dementia in diabetic individuals in observational studies. However, the ca......

JIF:8.049

Associations of combined healthy lifestyles with cancer morbidity and mortality among individuals with diabetes: results from five cohort studies in the USA, the UK and China

期刊: DIABETOLOGIA, 2022; 65 (12)

Aims/hypothesis Cancer has contributed to an increasing proportion of diabetes-related deaths, while lifestyle management is the cornerstone of both d......

JIF:8.049

Metagenomic analysis reveals crosstalk between gut microbiota and glucose-lowering drugs targeting the gastrointestinal tract in Chinese patients with type 2 diabetes: a 6 month, two-arm randomised trial

期刊: DIABETOLOGIA, 2022; 65 (10)

Aims/hypothesis The use of oral glucose-lowering drugs, particularly those designed to target the gut ecosystem, is often observed in association with......

JIF:8.049

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