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Antibodies as tools in cytokine discovery and usage for diagnosis and therapy of inflammatory diseases

期刊: EUROPEAN CYTOKINE NETWORK, 2023; 34 (1)

Polyclonal antisera from patients have been at the basis of the description of autoimmune diseases and today monoclonal antibodies are widely used in ......

NLRP12 reduces proliferation and inflammation of rheumatoid arthritis fibroblast-like synoviocytes by regulating the NF-kappa B and MAPK pathways

期刊: EUROPEAN CYTOKINE NETWORK, 2021; 32 (2)

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by abnormal synovial hyperplasia and the release of inflammatory cyto......

Serum Th17 and TNF-alpha distinguish between patients with occult hepatitis B infection, chronic hepatitis B infection and healthy individuals

期刊: EUROPEAN CYTOKINE NETWORK, 2021; 32 (2)

Chronic hepatitis B (CHB) is classified into five phases based on virus-host interactions: immune tolerance, immune clearance, inactive carrier state,......

Upregulated Tie2 expression in plasma: a potential non-invasive biomarker for the diagnosis of breast cancer

期刊: EUROPEAN CYTOKINE NETWORK, 2021; 32 (2)

Breast cancer is by far the most common malignancy found in women and causes a significant public health problem around the world. Early diagnosis of ......

Effect of white tea consumption on serum leptin, TNF-alpha and UCP1 gene expression in ovariectomized rats

期刊: EUROPEAN CYTOKINE NETWORK, 2021; 32 (2)

Background: Obesity and dyslipidemia due to estrogen deficiency are among the important health problems in menopausal women. Increasing evidence repor......

Serum levels of nesfatin-1 and irisin in obese children

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (1)

Background:Along with the developing technology in the modern age, physical activity had decreased considerably in children and adolescents alike with......

Comparing effects of low glycemic index/high-fat, high-calorie diet and high-fat, high-calorie diet on cytokine levels of patients with cystic fibrosis: A randomized controlled clinical trial

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (1)

The importance of the host inflammatory response, as a central pathological feature of cystic fibrosis, is well recognized. Additionally, hyperglycemi......

Increase of circulating inflammatory molecules in preeclampsia, an update

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (1)

Special hormonal and immunological changes are required for normal pregnancy continuation. To escape from rejection by the maternal immune system, pre......

When wrinkles appear on the immune system can it be reversed?

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (1)

During aging, physiological and physical frailty occur, which is accompanied by a decline in adaptive and innate immunity, termed 'immunosenescence' c......

Association of Interleukin-33 with Recurrent Pregnancy Loss in Egyptian Women

期刊: EUROPEAN CYTOKINE NETWORK, 2022; 33 (2)

Background A successful pregnancy requires a distinct and complex immunological state. Cytokines appear to be critical for the establishment of a tole......

JIF:2.632

Quantification of angiogenic factors and their clinicopathological associations in breast cancer

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (2)

Introduction and aim Breast cancer (BC) is one of the top three common cancers in women, responsible for nearly one-third of all new cancer diagnoses.......

IL-17A induction of ADAMTS-5 in differentiated THP-1 cells is modulated by the ERK signaling pathway

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (2)

Atherosclerosis is initiated when lipoproteins are trapped by proteoglycans in the arterial intima. Macrophages play a vital role in this disease, esp......

Natural cannabinoids suppress the cytokine storm in sepsis-likein vitromodel

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (2)

Natural cannabinoids may have beneficial effects on various tissues and functions including a positive influence on the immune system and the inflamma......

Interleukin-6 and severe COVID-19: a systematic review and meta-analysis

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (2)

Background Evidence links COVID-19 severity to hyper-inflammation. Treatment with tocilizumab, a monoclonal antibody directed against the interleukin-......

Preconceptional immunization with an allergen inhibits offspring thymic Th17 cells maturation without influence on Th1 and Th2 cells

期刊: EUROPEAN CYTOKINE NETWORK, 2020; 31 (3)

The mechanisms through which maternal immunization can modulate offspring thymic maturation of lymphocytes are not fully understood. Here, we aimed to......

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