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Advances in Circular RNA and Its Applications

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (6)

Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, un......

JIF:3.576

SJMHE1 protects against excessive iodine-induced pyroptosis in human thyroid follicular epithelial cells through a toll-like receptor 2-dependent pathway

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (4)

To elucidate the effect of Schistosoma japonicum peptide (SJMHE1) on pyroptosis in thyroid follicular epithelial cells (TFCs) induced by excessive iod......

JIF:3.576

Immune Reconstitution in Pediatric Aplastic Anemia after Allogeneic Hematopoietic Stem-cell Transplantation

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

Background: Previous studies had revealed that immune reconstitution (IR) after allogeneic hematopoietic stem-cell transplantation (allo-HSCT) affecte......

JIF:3.576

Liquid Enteral Nutrients Alter the Pharmacokinetics of Orally Administered Carbamazepine in Rats

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

The interaction between enteral nutrients (ENs) and drugs co-administered through a nasogastric (NG) tube reportedly affects the absorption and result......

JIF:3.576

The role of circular RNA in Diabetic Nephropathy

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

Diabetic nephropathy (DKD) is the most common chronic microvascular complication of diabetes. About 20%-40% of diabetics develop DKD, which eventually......

JIF:3.576

Hsa_circRNA_0040462: a sensor of cells' response to CAP treatment with double-edged roles on breast cancer malignancy

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (4)

Cold atmospheric plasma (CAP) represents a novel onco-therapeutic approach that has demonstrated its efficacy in many types of tumors. The efficacy of......

JIF:3.576

SIRT1: A Novel Protective Molecule in Pre-eclampsia

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (6)

Pre-eclampsia is a severe pregnant complication, mainly characterized by insufficient trophoblast invasion, impaired uterine spiral artery remodeling,......

JIF:3.576

Oridonin represses epithelial-mesenchymal transition and angiogenesis of thyroid cancer via downregulating JAK2/STAT3 signaling

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (6)

Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens, has been reported to exert anticancer activity in various cancers. However, the mo......

JIF:3.576

Bioinformatic Analysis Identifying PSMB 1/2/3/4/6/8/9/10 as Prognostic Indicators in Clear Cell Renal Cell Carcinoma

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

Renal cancer incidence has been increasing across the world, clear cell renal cell carcinoma (ccRCC) represents the major subtype of renal cancer. The......

JIF:3.576

Cell death mechanisms induced by synergistic effects of halofuginone and artemisinin in colorectal cancer cells

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (1)

Our previous study found that the combination of halofuginone (HF) and artemisinin (ATS) synergistically arrest colorectal cancer (CRC) cells at the G......

JIF:3.576

Expression Landscape and Functional Roles of HOXA4 and HOXA5 in Lung Adenocarcinoma

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (3)

Background: The role of HOXA family genes in the occurrence and progression of a variety of human cancers has been scatteredly reported. However, ther......

JIF:3.576

Normalisation of High Bone Remodelling due to Oestrogen Deficiency by Traditional Chinese Formulation Kang Shuai Lao Pian in Ovariectomised Rats

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (11)

Postmenopausal osteoporosis transpires due to excessive osteoclastic bone resorption and insufficient osteoblastic bone formation in the presence of o......

JIF:3.576

Maternal Th17/Treg Cytokines and Small Extracellular Vesicles in Plasma as Potential Biomarkers for Preeclampsia

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (11)

Preeclampsia is one of the most serious pregnancy complications. It may be caused by immunological changes in the early placental microenvironment. Th......

JIF:3.576

Comparison of the effects of dexmedetomidine and propofol on hypothermia in patients under spinal anesthesia: a prospective, randomized, and controlled trial

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

Background: Redistribution hypothermia caused by vasodilation during anesthesia is the primary cause of perioperative hypothermia. Propofol exerts a d......

JIF:3.576

Prognostic significance of histological grade in low-risk endometrial cancer

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (13)

Objective: Investigate the risk factors for recurrence in patients with low-risk endometrial cancer.Method: A retrospective review was performed to id......

JIF:3.576

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