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Evidence that PKC alpha inhibition in Dalton's Lymphoma cells augments cell cycle arrest and mitochondrial-dependent apoptosis

期刊: LEUKEMIA RESEARCH, 2022; 113 ()

Protein kinase C alpha (PKC alpha), belonging to ser/thr protein kinase, perform various biological functions. Over expression of PKC alpha has been o......

JIF:2.077

Clinical characteristics and survival outcomes of newly diagnosed multiple myeloma patients presenting with extramedullary disease: A retrospective study

期刊: LEUKEMIA RESEARCH, 2022; 115 ()

The aim of study was to assess the clinical characteristics, survival outcomes of newly diagnosed multiple myeloma (NDMM) patients with extramedullary......

JIF:2.077

Mantle cell lymphoma and the evidence of an immature lymphoid component

期刊: LEUKEMIA RESEARCH, 2022; 115 ()

Mantle cell lymphoma (MCL) is a rare B cell malignancy. The classical MCL subtype is positive for translocation t (11;14), SOX11 expression, and chara......

JIF:2.077

LncRNA CCAT2 expression at diagnosis predicts imatinib response in chronic phase chronic myeloid leukemia patients

期刊: LEUKEMIA RESEARCH, 2022; 116 ()

Long noncoding RNAs (lncRNAs) are identified as key players in the initiation, development, and prognosis of chronic myeloid leukemia (CML). Some lncR......

JIF:2.077

PTPN11 mutations in adult acute myeloid leukaemia: Prevalence and clinical implications in the context of NPM1 mutation

期刊: LEUKEMIA RESEARCH, 2022; 118 ()

More than 90% of NPM1-mutated acute myeloid leukaemia (NPM1mut AML) patients have been determined to harbour other known concurrent mutations. However......

JIF:2.077

Effect of cumulative daunorubicin dose on cardiotoxicity after allogeneic stem cell transplantation

期刊: LEUKEMIA RESEARCH, 2022; 121 ()

Cardiotoxicity after allogeneic stem cell transplantation (SCT) is associated with a high rate of mortality and worsening quality of life. The relatio......

JIF:2.077

Measurable residual disease by flow cytometry in acute myeloid leukemia is prognostic, independent of genomic profiling

期刊: LEUKEMIA RESEARCH, 2022; 123 ()

Measurable residual disease (MRD) assessment provides a potent indicator of the efficacy of anti-leukemic therapy. It is unknown, however, whether int......

JIF:2.077

Molecular evaluation of gene mutation profiles and copy number variations in pediatric acute myeloid leukemia

期刊: LEUKEMIA RESEARCH, 2022; 122 ()

Background: The objectives of this study were to investigate the mutation profiles of targeted genes and copy number variations (CNVs) in normal cytog......

JIF:2.077

Do patients with haematological malignancies suffer financial burden? A cross-sectional study of patients seeking care through a publicly funded healthcare system

期刊: LEUKEMIA RESEARCH, 2022; 112 ()

Background: It is increasingly appreciated that some patients with cancer will experience financial burden due to their disease but little is known sp......

JIF:2.077

The association of genetic alterations with response rate in newly diagnosed chronic myeloid leukemia patients

期刊: LEUKEMIA RESEARCH, 2022; 114 ()

Genetic differences may be associated with the response to tyrosine kinase inhibitor (TKI) in patients with chronic myeloid leukemia (CML). In this st......

JIF:2.077

Effects of conventional interventions on early-stage primary cutaneous marginal zone lymphoma: A population-based study

期刊: LEUKEMIA RESEARCH, 2022; 114 ()

Background: Information on the outcomes and treatments of early-stage (I/II) primary cutaneous marginal zone lymphoma (PCMZL) is limited. This study a......

JIF:2.077

Midkine inhibitor (iMDK) induces apoptosis of primary effusion lymphoma via G2/M cell cycle arrest

期刊: LEUKEMIA RESEARCH, 2022; 116 ()

Primary effusion lymphoma (PEL) is an aggressive B-cell non-Hodgkin lymphoma in immunocompromised individuals such as AIDS patients. PEL shows a poor ......

JIF:2.077

Treatment Failure in Acute Myeloid Leukemia: Focus on the Role of Extracellular Vesicles

期刊: LEUKEMIA RESEARCH, 2022; 112 ()

Acute myeloblastic leukemia (AML) is one of the most common types of blood malignancies that results in an AML-associated high mortality rate each yea......

JIF:2.077

Evaluation of isatuximab in patients with soft-tissue plasmacytomas: An analysis from ICARIA-MM and IKEMA

期刊: LEUKEMIA RESEARCH, 2022; 122 ()

The Phase 3 ICARIA-MM (NCT02990338) and IKEMA (NCT03275285) studies demonstrated that isatuximab (Isa) plus pomalidomide (P) and dexamethasone (d; Isa......

JIF:2.077

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