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Gene and transgenics nomenclature for the laboratory axolotl-Ambystoma mexicanum

期刊: DEVELOPMENTAL DYNAMICS, 2022; 251 (6)

The laboratory axolotl (Ambystoma mexicanum) is widely used in biological research. Recent advancements in genetic and molecular toolkits are greatly ......

JIF:3.392

Revitalizing mouse diphyodontic dentition formation by inhibiting the sonic hedgehog signaling pathway

期刊: DEVELOPMENTAL DYNAMICS, 2022; 251 (5)

Background: Tooth regeneration depends on the longevity of the dental epithelial lamina. However, the exact mechanism of dental lamina regression has ......

JIF:3.392

Fate-mapping analysis of cochlear cells expressing Atoh1 mRNA via a new Atoh1(3*HA-P2A-Cre) knockin mouse strain

期刊: DEVELOPMENTAL DYNAMICS, 2022; 251 (7)

Background Atoh1 is recognized to be essential for cochlear hair cell (HC) development. However, Atoh1 temporal and spatial expression patterns remain......

JIF:3.392

The role of the protein tyrosine phosphatase SHP2 in ossification

期刊: DEVELOPMENTAL DYNAMICS, 2022; 251 (5)

SHP2, encoded by the PTPN11 gene, participates in multiple cell functions including cell proliferation, movement, and differentiation. PTPN11 loss-of-......

JIF:3.392

Delineating the roles of Grhl2 in craniofacial development through tissue-specific conditional deletion and epistasis approaches in mouse

期刊: DEVELOPMENTAL DYNAMICS, ; ()

Background The highly conserved Grainyhead-like (Grhl) family of transcription factors play critical roles in the development of the neural tube and c......

Eya2 expression during mouse embryonic development revealed by Eya2(lacZ) knockin reporter and homozygous mice show mild hearing loss

期刊: DEVELOPMENTAL DYNAMICS, ; ()

Background Eya2 expression during mouse development has been studied by in situ hybridization and it has been shown to be involved skeletal muscle dev......

Mechanism and restoration strategy of lysosomal abnormalities induced by urinary protein overload in proximal tubule epithelial cells

期刊: DEVELOPMENTAL DYNAMICS, ; ()

Background: Persistent elevated concentrations of urinary protein can destroy proximal tubule epithelial cells (PTECs) by inducing lysosomal abnormali......

Single-cell analysis of nonhuman primate preimplantation development in comparison to humans and mice

期刊: DEVELOPMENTAL DYNAMICS, ; ()

Background Genetic programs underlying preimplantation development and early lineage segregation are highly conserved across mammals. It has been sugg......

Nonframeshifting indel variations in polyalanine repeat of HOXD13 gene underlies hereditary limb malformation for two Chinese families

期刊: DEVELOPMENTAL DYNAMICS, ; ()

Background Polydactyly and syndactyly are the most common hereditary limb malformations. Molecular genetic testing is of great significance for heredi......

Maturation stage enamel defects in Odontogenesis-associated phosphoprotein (Odaph) deficient mice

期刊: DEVELOPMENTAL DYNAMICS, ; ()

Background Mutation in Odontogenesis-associated phosphoprotein (ODAPH) has been reported to cause recessive hypomineralized amelogenesis imperfecta (A......

Mouse spermatogenesis-associated protein 1 (SPATA1), an IFT20 binding partner, is an acrosomal protein

期刊: DEVELOPMENTAL DYNAMICS, 2020; 249 (4)

Background Intraflagellar transport is a motor-driven trafficking system that is required for the formation of cilia. Intraflagellar transport protein......

Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds

期刊: DEVELOPMENTAL DYNAMICS, 2020; 249 (6)

Background Cruciate ligament (CL) and patellar tendon (PT) are important elements of the knee joint, uniting femur, patella, and tibia into a single f......

GFPexpression pattern in pituitary and gonads under the control of nuclear progesterone receptor promoter in transgenic zebrafish

期刊: DEVELOPMENTAL DYNAMICS, 2020; 249 (11)

Background The nuclear progesterone receptor (Pgr) is a ligand-dependent transcription factor primarily responsible for mediating progesterone actions......

Dental and craniofacial defects in theCrtap(-/-)mouse model of osteogenesis imperfecta type VII

期刊: DEVELOPMENTAL DYNAMICS, 2020; 249 (7)

Background Inactivating mutations in the gene for cartilage-associated protein (CRTAP) cause osteogenesis imperfecta type VII in humans, with a phenot......

miR-199 family contributes to regulation of sonic hedgehog expression during craniofacial development

期刊: DEVELOPMENTAL DYNAMICS, 2020; 249 (9)

Background The frontonasal ectodermal zone (FEZ) is a signaling center that regulates patterned development of the upper jaw, and Sonic hedgehog (SHH)......

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