筛选条件 共查询到11条结果
排序方式
How to inhibit transforming growth factor beta safely in diabetic kidney disease

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2021; 30 (1)

Purpose of review Diabetic kidney disease (DKD) is a leading cause of mortality and morbidity in diabetes. This review aims to discuss the major featu......

Research progress of sirtuins in renal and cardiovascular diseases

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2021; 30 (1)

Purpose of review Sirtuins are a family of nicotinamide adenine dinucleotide+-dependent enzymes catalyzing target protein deacetylation to modulate ce......

Tubular effects of sodium-glucose cotransporter 2 inhibitors: intended and unintended consequences

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2020; 29 (5)

Purpose of review Sodium-glucose cotransporter 2 (SGLT2) inhibitors are antihyperglycemic drugs that act by inhibiting renal sodium-glucose cotranspor......

Targeting angiotensinogen with RNA-based therapeutics

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2020; 29 (2)

Purpose of review To summarize all available data on targeting angiotensinogen with RNA-based therapeutics as a new tool to combat cardiovascular dise......

Fluid management and bioimpedance study in peritoneal dialysis

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2019; 28 (1)

Purpose of review Maintaining euvolaemia is an essential yet challenging objective in management of patients on peritoneal dialysis. Optimal method to......

JIF:3.01

Immunohistochemistry for aldosterone synthase CYP11B2 and matrix-assisted laser desorption ionization imaging mass spectrometry for in-situ aldosterone detection

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2019; 28 (2)

Purpose of review Immunohistochemistry for aldosterone synthase (CYP11B2) has markedly provided a comprehensive picture of the adrenocortical diseases......

JIF:3.01

Enzymatic sources and physio-pathological functions of soluble (pro)renin receptor

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2018; 27 (2)

Purpose of review (Pro)renin receptor (PRR) belongs to type I transmembrane receptor family and binds both prorenin and renin, representing a potentia......

JIF:3.01

Renal effects of cytokines in hypertension

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2018; 27 (2)

Purpose of review Inflammatory cytokines contribute to the pathogenesis of hypertension through effects on renal blood flow and sodium handling. This ......

JIF:3.01

Role of corin in the regulation of blood pressure

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2017; 26 (2)

Purpose of review Corin is a transmembrane protease that activates atrial natriuretic peptide (ANP), an important hormone in regulating salt-water bal......

JIF:3.37

Dipeptidyl peptidase-4 inhibition and renoprotection: the role of antifibrotic effects

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2017; 26 (1)

Purpose of reviewThis article analyzes the potential beneficial effects of dipeptidyl peptidase (DPP)-4 inhibitors on renal diseases.Recent findingsTh......

JIF:3.37

The kallikrein-kinin system in diabetic kidney disease

期刊: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2017; 26 (5)

Purpose of review Diabetic kidney disease (DKD) is one of the most common complications in diabetes mellitus and accounts for a large proportion of cl......

JIF:3.37

共11条页码: 1/1页15条/页