期刊： CURRENT DRUG METABOLISM, 2021; 22 (6)
Background: Caesalpinia sappan L. is a traditional medicinal plant that is used to promote blood circulation and treat stroke in China. Protosappanin ......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (5)
Background: Both clotrimazole and ketoconazole have been verified to have an inhibitory effect on CYP3A4. hCE2 is an enzyme closely related to the sid......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (6)
Background: Pantoprazole and atorvastatin are often used jointly in the clinic. The drug-drug interaction of pantoprazole and atorvastatin is worthy o......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (6)
Obesity is a common nutritional disorder associated with a variety of chronic diseases, among them, type 2 diabetes (T2DM) has emerged as a serious wo......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (5)
Background: Fixed-dose combination of artemisinin and naphthoquine (NQ) is a new artemisinin-based combination therapy for the treatment of uncomplica......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (5)
Background: The role of multidrug resistance-associated protein 3 (Mrp3) in the transport of bile acid (BA) in drug-induced cholestasis has not been w......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (2)
Ovarian cancer (OC) is one of the deadliest gynecological malignancy. Epithelial ovarian cancer (EOC) is its most common form. OC has both, a poor pro......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (1)
Background: Alpiniae oxyphyllae Fructus (AOF), a traditional Chinese medicine (TCM), is widely used in the treatment of urinary, gastrointestinal and ......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (1)
Aims: This is a pharmacokinetic study of Salviae miltiorrhizae and ligustrazine hydrochloride injection. The study aimed to evaluate the mechanism of ......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (1)
Human cytochrome P450 enzyme 1A2 (CYP1A2) is one of the most important cytochrome P450 (CYP) enzymes in the liver, accounting for 13% to 15% of hepati......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (1)
Background: Erigeron breviscapus (Vant.)Hand-Mazz. is a plant species in the Compositae family. More than ten types of compounds-such as flavonoids, c......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (1)
Background: Many antibiotics have a high potential for interactions with drugs, as a perpetrator and/or victim, in critically ill patients, and partic......
期刊： CURRENT DRUG METABOLISM, 2021; 22 (3)
Background: Praziquantel (PZQ), which possesses an asymmetric center, is classified as a pyrazinoisoquinoline and has been the mainstay in the treatme......
