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Molecular interaction of cytotoxic anticancer analogues as inhibitors of beta-tubulin protein against UACC-62 melanoma cell

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (5)

In previous research, a series of cytotoxic anticancer analogues related to 2-acylamino-1,4-naphthoquinone derivatives has been demonstrated. As micro......

Binding of collagen gene products with titanium oxide

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (5)

Titanium is the only metal to which osteoblasts can adhere and on which they can grow and form bone tissue in vivo, resulting in a strong bond between......

circGFRA1 affects the sensitivity of triple-negative breast cancer cells to paclitaxel via the miR-361-5p/TLR4 pathway

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (5)

In recent years, the role of circular RNAs (circRNAs) in tumours has attracted widespread attention. Some circRNAs have been reported to play a role i......

Circular RNA hsa_circ_0102231 sponges miR-145 to promote non-small cell lung cancer cell proliferation by up-regulating the expression of RBBP4

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (1)

Circular RNAs (circRNAs) are important regulators in various cancers. Previous studies have found that hsa_circ_0102231 is an oncogene in lung adenoca......

LncRNA HEIH promotes cell proliferation, migration and invasion by suppressing miR-214-3p in gastric carcinoma

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (5)

The present study aimed to investigate the function of long non-coding RNA HEIH in gastric carcinoma (GC). Adjacent normal tissues and GC tissues were......

Silent information regulator type-1 mediates amelioration of inflammatory response and oxidative stress in lipopolysaccharide-induced acute respiratory distress syndrome

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (5)

Silent information regulator type-1 (SIRT1) is crucial during the development of acute respiratory distress syndrome (ARDS). We aimed to explore wheth......

Down-regulation of lncRNA SNHG5 relieves sepsis-induced acute kidney injury by regulating the miR-374a-3p/TLR4/NF-kappa B pathway

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (5)

Sepsis is an acute systemic infectious disease engendered by infectious factors, which can cause the dysfunction of multiple organs, including acute k......

BaeR participates in cephalosporins susceptibility by regulating the expression level of outer membrane proteins in Escherichia coli

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (1)

The two-component system BaeSR participates in antibiotics resistance of Escherichia coli. To know whether the outer membrane proteins involve in the ......

CircRNA_0092516 regulates chondrocyte proliferation and apoptosis in osteoarthritis through the miR-337-3p/PTEN axis

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (4)

The dysregulation of circular RNAs (circRNAs) has been identified in various human diseases. Here, we probed into the potential mechanism of circRNA_0......

miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (2)

Cerebral ischemia/reperfusion (I/R) injury is an obstacle in treating ischemic stroke effectively. miR-98-5p has been reported to have the ability of ......

Upregulation of circ_0000142 promotes multiple myeloma progression by adsorbing miR-610 and upregulating AKT3 expression

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (3)

Circular RNAs (circRNAs) play an important regulatory role in a variety of malignancies. Nevertheless, the role of circ_0000142 in multiple myeloma (M......

Molecular and functional characaterization of the novel odorant-binding protein gene AccOBP10 from Apis cerana cerana

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (2)

Odorant-binding proteins (OBPs) play an important role in odour perception and transport in insects. However, little is known about whether OBPs perfo......

Cd(II)-binding transcriptional regulator interacts with isoniazid and regulates drug susceptibility in mycobacteria

期刊: JOURNAL OF BIOCHEMISTRY, 2021; 169 (1)

It is urgent to understand the regulatory mechanism of drug resistance in widespread bacterial pathogens. In Mycobacterium tuberculosis, several trans......

Downregulated long non-coding RNA LINC01093 in liver fibrosis promotes hepatocyte apoptosis via increasing ubiquitination of SIRT1

期刊: JOURNAL OF BIOCHEMISTRY, 2020; 167 (5)

The apoptosis of hepatocytes contributes to the activation of hepatic stellate cells (HSCs), thus promoting the accumulation of extracellular matrix p......

MicroRNA-1271-5p inhibits cell proliferation and enhances radiosensitivity by targeting CDK1 in hepatocellular carcinoma

期刊: JOURNAL OF BIOCHEMISTRY, 2020; 167 (5)

This study aims to determine whether miR-1271-5p inhibits cell proliferation and enhances the radiosensitivity by targeting cyclin-dependent kinase 1 ......

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