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Conophylline Suppresses Angiotensin II-Induced Myocardial Fibrosis In Vitro via the BMP4/JNK Pathway

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 171 (3)

We studied the effects and mechanisms of action of conophylline in different concentrations in the original in vitro model of myocardial fibrosis (tre......

Metabolic Disorders and Mineral Density of the Bone Tissue in the Early Pathogenesis of Osteonecrosis: Study on Rabbits with Steroid-Induced Osteonecrosis

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (6)

The relationship between the appearance of bone metabolism disorders and the onset of steroid-induced osteonecrosis remains unclear. We studied the ti......

Perfluorocarbon Protects against Lipopolysaccharide-Induced Apoptosis of Endothelial Cells in Pulmonary Microvessels

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (4)

This study was aimed to explore the effect and mechanisms of action of perfluorocarbon on LPS-induced apoptosis of pulmonary microvascular endothelial......

Effects of Birinapant on Proliferation and Invasion of MGC-803 Gastric Cancer Cells and Mechanism Underlying These Effects

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 171 (1)

We studied the effects of birinapant, a mimetic of the second mitochondria-derived activator of caspase (SMAC), on invasion and proliferation of MGC-8......

Expression of Genes Encoding Nuclear Factors PPAR gamma, LXR beta, and ROR alpha in Epicardial and Subcutaneous Adipose Tissues in Patients with Coronary Heart Disease

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (5)

The nuclear factors PPAR gamma, ROR alpha, and LXR beta are involved in transcriptional control of adipogenesis and implicated in glucose and lipid me......

Microarray Analysis of Novel Genes Involved in Nasopharyngeal Carcinoma

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (5)

Nasopharyngeal carcinoma (NPC) is an epithelial cancer associated with Epstein-Barr virus. Despite NPC is a widespread malignancy, little is known abo......

Expression and Clinical Significance of OX40 and OX40L mRNA in Hepatocellular Carcinoma

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (4)

In a retrospective study, the expression of mRNA of membrane receptor OX40 and its ligand OX40L in liver tissues was analyzed in 34 patients with hepa......

Effective Model of Food Allergy in Mice Sensitized with Ovalbumin and Freud's Adjuvant

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 171 (3)

To better explore the pathophysiology of FA and its therapy, we aimed to establish a simple and practicable FA model with Freund's adjuvant and introd......

Activation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 171 (3)

The study examines the problem whether pyroptosis of U87-MG glioblastoma cells can result from activation of Ca2+/calmodulin-dependent protein kinase ......

Comparative Study of Wound-Healing Activity of Dihydroquercetin Pseudopolymorphic Modifications

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (4)

Wound-healing activity of the crystalline form of dihydroquercetin and its microtubular pseudopolymorphic modification obtained by crystal engineering......

Clinical and Experimental Evaluation of Diagnostic Significance of Alpha-Fetoprotein and Osteopontin at the Early Stage of Hepatocellular Cancer

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (3)

We evaluated the possibility of using an experimental model of hepatocellular carcinoma to study oncomarkers of primary liver cancer and compared the ......

Low-Dose Ozone Therapy Improves Sleep Quality in Patients with Insomnia and Coronary Heart Disease by Elevating Serum BDNF and GABA

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 170 (4)

We studied the effects of low-dose ozone therapy on the sleep quality of patients with coronary heart disease (CHD) and insomnia by measuring the leve......

Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2021; 171 (2)

We studied metastasis-promoting effect of transmembrane protease TMPRSS4 on mismatch repair (MMR)-deficient colorectal cancer liver metastasis in BALB......

Effect of Humic Acids from Lowland Peat on Endurance of Rats in Forced Swim Test in Relation to Serum Lactate and Corticosterone

期刊: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2020; 169 (6)

The study substantiated the possibility of using peat humic acids for improving endurance during extreme physical exertion. The mature outbred Wistar ......

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