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Spatiotemporal Changes in the Gene Expression Spectrum of the beta 2 Adrenergic Receptor Signaling Pathway in the Lungs of Rhesus Monkeys

期刊: LUNG, 2021; 199 (1)

Objective beta 2 adrenergic receptor (ADRB2) agonists mainly participate in regulation of airway function through the ADRB2-G protein-adenylyl cyclase......

Analyzing the Effect of Vitronectin on Cell Growth and Mesenchymal-Epithelial Transition of Pulmonary Fibroblast Cells

期刊: LUNG, 2021; 199 (4)

Purpose Vitronectin (VTN), a multifunctional glycoprotein, is involved in various biological and pathological processes. The purpose of this study was......

Inhibition of MicroRNA-214 Alleviates Lung Injury and Inflammation via Increasing FGFR1 Expression in Ventilator-Induced Lung Injury

期刊: LUNG, 2021; 199 (1)

Purpose Ventilator-induced lung injury (VILI) is an additional inflammatory injury caused by mechanical ventilation (MV). This study aimed to determin......

Current Status and Future Directions of Chronic Cough in China

期刊: LUNG, 2020; 198 (1)

Chronic cough is one of the most common complaints for which patients in China seek medical attention. However, there are no nationwide data on the pr......

High Systemic Immune-Inflammation Index (SII) Represents an Unfavorable Prognostic Factor for Small Cell Lung Cancer Treated with Etoposide and Platinum-Based Chemotherapy

期刊: LUNG, 2020; 198 (2)

Purpose Systemic immune-inflammation index (SII) has been demonstrated to be closely associated with prognosis of a series of solid tumors. However, i......

High Expression of CARM1 Inhibits Lung Cancer Progression by Targeting TP53 by Regulating CTNNB1

期刊: LUNG, 2020; 198 (2)

Objective To explore the role of CARM1 in lung cancer (LC) and its relationship with TP53 and CTNNB1. Methods Lung cells H1299 and PC14 were randomly ......

Needle Aspiration Versus Closed Thoracostomy in the Treatment of Spontaneous Pneumothorax: A Meta-analysis

期刊: LUNG, 2020; 198 (2)

Purpose To compare the effectiveness and safety between needle aspiration (NA) and closed thoracostomy (CT) method in adult spontaneous pneumothorax (......

Resveratrol Attenuates Intermittent Hypoxia-Induced Lung Injury by Activating the Nrf2/ARE Pathway

期刊: LUNG, 2020; 198 (2)

Purpose Obstructive sleep apnea (OSA) is associated with lung injury. As a novel pathophysiological hallmark of OSA, chronic intermittent hypoxia (CIH......

Elevated Circulating CD4(+)CD25(+)CD127(-/low) Regulatory T Cells in Patients with Non-asthmatic Eosinophilic Bronchitis

期刊: LUNG, 2020; 198 (3)

Purpose Non-asthmatic eosinophilic bronchitis (NAEB) is a common cause of chronic cough. It is characterized by sputum eosinophilia like asthma but la......

Increased Th17 and Th22 Cell Percentages Predict Acute Lung Injury in Patients with Sepsis

期刊: LUNG, 2020; 198 (4)

Purpose This study was conducted to investigate the percentages of Th22 and Th17 cells in the peripheral blood of septic patients with and without acu......

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