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Discovery of myricetin as an inhibitor against Streptococcus mutans and an anti-adhesion approach to biofilm formation

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2021; 311 (4)

Streptococcus mutans (S. mutans) are cariogenic microorganisms. Sortase A (SrtA) is a transpeptidase that attaches Pac to the cell surface. The biofil......

A novel mutation of walK confers vancomycin-intermediate resistance in methicillin-susceptible Staphylococcus aureus

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2021; 311 (2)

With the treatment failure by vancomycin and poor clinical outcomes, the emergence and spread of vancomycin intermediate-resistant Staphylococcus aure......

LincRNA-Cox2 regulates IL6/JAK3/STAT3 and NF-kappa B P65 pathway activation in Listeria monocytogenes-infected RAW264.7 cells

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2021; 311 (5)

Listeria monocytogenes (Lm) can lead to high mortality rates relative to other foodborne pathogens. Lm-induced inflammation is partly characterized by......

hns mRNA downregulates the expression of galU and attenuates the motility of Salmonella enterica serovar Typhi

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2021; 311 (6)

Recently, multiple bifunctional RNAs have been discovered, which can both be translated into proteins and play regulatory roles. hns encodes the globa......

Prevalence, genomic characteristics, and transmission dynamics of mcr-1-positive Salmonella enterica Typhimurium from patients with infectious diarrhea

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2021; 311 (4)

Background: Previous studies reported the prevalence of mcr-1 among clinical infected Salmonella isolates in China. However, the transmission dynamics......

Reverse vaccinology approach for the identifications of potential vaccine candidates against Salmonella

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2021; 311 (5)

Salmonella is a leading cause of foodborne pathogen which causes intestinal and systemic diseases across the world. Vaccination is the most effective ......

sncRNAs packaged by Helicobacter pylori outer membrane vesicles attenuate IL-8 secretion in human cells

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (1)

Bacterial outer membrane vesicles (OMVs) play a vital role in the mechanism of host-pathogen communication, while emerging evidence suggests that OMVs......

Escherichia coli strains producing a novel Shiga toxin 2 subtype circulate in China

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (1)

Shiga toxin (Stx) is the key virulence factor in Shiga toxin producing Escherichia coli (STEC), which can cause diarrhea and hemorrhagic colitis with ......

Co-existence of Citrobacter freundii exacerbated Pseudomonas aeruginosa infection in vivo

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (1)

The presence of bacterial species other than the pathogen at infection site can affect the progression of a bacterial infection. Based on the fact tha......

Genotypic differences in CC224, CC363, CC449 and CC446 of Moraxella catarrhalis isolates based on whole genome SNP, MLST and PFGE typing

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (1)

Understanding the evolutionary path of M. catarrhalis from macrolide-susceptible to macrolide-resistant organism, is important for hindering macrolide......

Over-expression of Tgs1 in Mycobacterium marinum enhances virulence in adult zebrafish

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (1)

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), can persist in the host for decades without causing TB symptoms and can ca......

A novel type I toxin-antitoxin system modulates persister cell formation in Staphylococcus aureus

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (2)

A plethora of toxin-antitoxin systems exist in bacteria and has multilateral roles in bacterial pathogenesis and virulence. Toxin-antitoxin systems ha......

The Treponema pallidum outer membrane protein Tp92 activates endothelial cells via the chemerin/CMKLR1 pathway

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (3)

Endothelium damage caused by Treponema pallidum is the key step in the systemic dissemination and pathophysiology of syphilis, particularly cardiovasc......

Novel role of the phosphatidylinositol phosphatase Sac1 in membrane homeostasis and polarized growth in Candida albicans

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (4)

Phosphoinositides (PIPs) are one kind of membrane components functioning in many intracellular processes, especially in signaling transduction and mem......

The distribution of mutations and hotspots in transcription regulators of resistance-nodulation-cell division efflux pumps in tigecycline non-susceptible Acinetobacter baumannii in China

期刊: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020; 310 (8)

Objective: Acinetobacter baumannii has emerged as a problematic hospital pathogen and tigecycline is among the few remaining antibiotics retaining act......

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