Estrogen-related receptor gamma (ERR gamma), a member of the orphan nuclear receptor family, is a key mediator in cellular metabolic processes and ene......
Increasing evidence suggests the role of miR-449a in the regulation of tumorigenesis and autophagy. Autophagy plays an important role in the malignanc......
期刊： BMB REPORTS, 2020; 53 (12)
The N-myc downstream regulated gene (NDRG) family members are dysregulated in several tumors. Functionally, NDRGs play an important role in the malign......
Alpha-fetoprotein (AFP) is one of the most commonly used and reliable biomarkers for Hepatocellular carcinoma (HCC). However, the underlying mechanism......
Metastasis is the main culprit of the great majority of cancer-related deaths. However, the complicated process of the invasion-metastasis cascade rem......
期刊： BMB REPORTS, 2020; 53 (10)
T-cell-based cancer immunotherapies, such as immune checkpoint blockers (ICBs) and chimeric antigen receptor (CAR)-T-cells, have significant anti-tumo......
Circular RNAs (circRNAs), one kind of non-coding RNA, have been reported as critical regulators for modulating gene expression in cancer. In this stud......
We investigated the effects of physalin A, B, D, and F on osteoclastogenesis induced by receptor activator of nuclear factor kappa B ligand (RANKL). T......
Our previous study found that two novel cancer-related genes, PRR11 and SKA2, constituted a classic gene pair that was regulated by p53 and NF-Y in lu......
RAD51 recombinase plays a critical role in homologous recombination and DNA damage repair. Here we showed that expression of RAD51 is frequently upreg......
Chemoresistance is the primary obstacle in the treatment of locally advanced and metastatic nasopharyngeal carcinoma (NPC). Recent evidence suggests t......
Keloids are the most common pathological form of trauma healing, with features that seriously affect appearance and body function, are difficult to tr......
