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Circulating Exosomes from Mice with LPS-Induced Bone Loss Inhibit Osteoblast Differentiation

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (2)

Osteoimmunology focuses on the intermodulation between bone and the immune system. Lipopolysaccharide (LPS)induced bone loss models are commonly used ......

JIF:3.86

Neuregulin 4 Attenuates Osteoarthritis Progression by Inhibiting Inflammation and Apoptosis of Chondrocytes in Mice

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 110 (1)

Osteoarthritis (OA) is characterized by chondrocyte apoptosis and increased degradation of type II collagen. Inflammation is one of the major risk fac......

JIF:3.86

Suture Cells in a Mechanical Stretching Niche: Critical Contributors to Trans-sutural Distraction Osteogenesis

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 110 (3)

Trans-sutural distraction osteogenesis has been proposed as an alternative technique of craniofacial remodelling surgery for craniosynostosis correcti......

JIF:3.86

Specific Characteristic of Hyperplastic Callus in a Larger Cohort of Osteogenesis Imperfecta Type V

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 110 (4)

Hyperplastic callus (HPC) is the most conspicuous features of osteogenesis imperfecta (OI) type V, of which accurate diagnosis and treatment are facin......

JIF:3.86

The Role of TAK1 in RANKL-Induced Osteoclastogenesis

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (1)

Bone remodelling is generally a dynamic process orchestrated by bone-resorbing osteoclasts and bone-forming osteoblasts. Osteoclasts are the only cell......

JIF:3.86

Inactivation of Ihh in Sp7-Expressing Cells Inhibits Osteoblast Proliferation, Differentiation, and Bone Formation, Resulting in a Dwarfism Phenotype with Severe Skeletal Dysplasia in Mice

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (5)

Indian hedgehog (Ihh) is an indispensable paracrine factor for proper tissue patterning, skeletogenesis, and cellular proliferation. Recent genetic st......

JIF:3.86

Vestigial-Like 3 Plays an Important Role in Osteoblast Differentiation by Regulating the Expression of Osteogenic Transcription Factors and BMP Signaling

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (3)

Our previous gene profiling analysis showed that the transcription cofactor vestigial-like 3 (VGLL3) gene expression was upregulated by mechanical ten......

JIF:3.86

Silibinin Can Promote Bone Regeneration of Selenium Hydrogel by Reducing the Oxidative Stress Pathway in Ovariectomized Rats

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 110 (6)

Osteoporosis-related bone defects are a major public health concern. Considering poor effects of a singular pharmacological treatment, many have sough......

JIF:3.86

Parathyroid Hormone (1-34) Attenuates Cartilage Degradation and Preserves Subchondral Bone Micro-architecture in Rats with Patella Baja-Induced-Patellofemoral Joint Osteoarthritis

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (1)

Several studies have revealed that PTH1-34 may possess the potential for treating osteoarthritis (OA) and osteoporosis. However, no study has yet dete......

JIF:3.86

Microparticles from Hyperphosphatemia-Stimulated Endothelial Cells Promote Vascular Calcification Through Astrocyte-Elevated Gene-1

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (1)

Endothelial microparticles (EMPs) can be released in chronic kidney disease (CKD). Plasma concentration of high inorganic phosphate (HP) is considered......

JIF:3.86

Knee Loading Enhances the Migration of Adipose-Derived Stem Cells to the Osteoarthritic Sites Through the SDF-1/CXCR4 Regulatory Axis

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (2)

Osteoarthritis (OA) is a whole joint disorder that is characterized by cartilage damage and abnormal remodeling of subchondral bone. Injecting adipose......

JIF:3.86

Odontogenesis-Associated Phosphoprotein (ODAPH) Overexpression in Ameloblasts Disrupts Enamel Formation via Inducing Abnormal Mineralization of Enamel in Secretory Stage

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 111 (6)

Odontogenesis-associated phosphoprotein (ODAPH) is a recently discovered enamel matrix protein. Our previous study demonstrated that knockouting out O......

JIF:3.86

Clinical, Biochemical, Radiological, Genetic and Therapeutic Analysis of Patients with COMP Gene Variants

期刊: CALCIFIED TISSUE INTERNATIONAL, 2022; 110 (3)

Pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia type 1 (MED1) are two rare skeletal disorders caused by cartilage oligomeric matrix pro......

JIF:3.86

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