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A Smart Nanoplatform with Photothermal Antibacterial Capability and Antioxidant Activity for Chronic Wound Healing

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (13)

Chronic wounds, such as the diabetic ulcer wounds have serious effect on people's lives, and can even lead to death. Diabetic ulcer wounds are differe......

Near-Infrared Light-Regulated Drug-Food Homologous Bioactive Molecules and Photothermal Collaborative Precise Antibacterial Therapy Nanoplatform with Controlled Release Property

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (16)

Herein, a collaborative precise antibacterial wound healing therapy nanoplatform integrating drug-food homologous bioactive molecule (cinnamaldehyde, ......

In Situ Construction of Functional Assemblies in Living Cells for Cancer Therapy

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (14)

Peptide-based materials hold great promise for various biomedical applications and have drawn increasing attention over the past five years. Despite t......

Guiding the Patterned Growth of Neuronal Axons and Dendrites Using Anisotropic Micropillar Scaffolds

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (12)

The patterning of axonal and dendritic growth is an important topic in neural tissue engineering and critical for generating directed neuronal network......

Cationic Tricyclic AIEgens for Concomitant Bacterial Discrimination and Inhibition

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (12)

New ionic compounds with aggregation-induced emission (AIE) feature has been widely studied. These AIE-based luminogens (AIEgens) not only effectively......

Rationally Designed, Self-Assembling, Multifunctional Hydrogel Depot Repairs Severe Spinal Cord Injury

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (13)

Following severe spinal cord injury (SCI), dysregulated neuroinflammation causes neuronal and glial apoptosis, resulting in scar and cystic cavity for......

Improved Small Extracellular Vesicle Secretion of Rat Adipose-Derived Stem Cells by Microgrooved Substrates through Upregulation of the ESCRT-III-Associated Protein Alix

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (16)

Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) hold great potential for regenerative therapies and have received considerable r......

Bioactive Decellularized Extracellular Matrix Derived from 3D Stem Cell Spheroids under Macromolecular Crowding Serves as a Scaffold for Tissue Engineering

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (11)

Scaffolds for tissue engineering aim to mimic the native extracellular matrix (ECM) that provides physical support and biochemical signals to modulate......

Biodegradability of Micro/Nanomotors: Challenges and Opportunities

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (13)

Micro/nanomotors (MNMs) are miniature machines that can convert chemical or external energy into their own mechanical motions. In previous decades, si......

Insights into Mechanism of A beta(42) Fibril Growth on Surface of Graphene Oxides: Oxidative Degree Matters

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (16)

The filamentous beta-amyloid deposition has been regarded as the hallmark pathology of Alzheimer's disease (AD). Nanomaterials such as graphene oxides......

Squaramide-Based Supramolecular Materials Drive HepG2 Spheroid Differentiation

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (11)

A major challenge in the use of HepG2 cell culture models for drug toxicity screening is their lack of maturity in 2D culture. 3D culture in Matrigel ......

An Engineered Protein Adhesive with Properties of Tissue Integration and Controlled Release for Efficient Cartilage Repair

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (12)

Cartilage damage is a prevalent health concern among humans. The inertness of cartilage, the absence of self-healing properties, and the lack of appro......

pH-Sensitive, Cerebral Vasculature-Targeting Hydroxyethyl Starch Functionalized Nanoparticles for Improved Angiogenesis and Neurological Function Recovery in Ischemic Stroke

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (12)

Angiogenesis, an essential restorative process following ischemia, is a promising therapeutic approach to improve neurological deficits. However, over......

Catalytic-Enhanced Lactoferrin-Functionalized Au-Bi2Se3 Nanodots for Parkinson's Disease Therapy via Reactive Oxygen Attenuation and Mitochondrial Protection

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (13)

Overexpression of reactive oxygen species in the substantia nigra pars compacta destroys dopaminergic neurons and accelerates the pathological process......

Influence of the Modulation of the Protein Corona on Gene Expression Using Polyethylenimine (PEI) Polyplexes as Delivery Vehicle

期刊: ADVANCED HEALTHCARE MATERIALS, 2021; 10 (13)

The protein corona can significantly modulate the physicochemical properties and gene delivery of polyethylenimine (PEI)/DNA complexes (polyplexes). T......

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