期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 158 ()
Melanoma anti-tumor therapy remains a challenge. SiRNA-based therapies provide a powerful means, but limitations remain in its pharmaceutical applicat......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 161 ()
In our previous study, a novel cell penetrating peptide (CPP) R7 (Arg-Arg-Arg-Arg-Arg-Trp-Trp, RRRRRWW) has been developed to help cellular internaliz......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 161 ()
Though polyurethane (PU) hydrogel had great potential in topical drug delivery system, drug skin delivery behavior from hydrogel and the underlying mo......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 161 ()
UDP-glucuronosyltransferase 1A9 (UGT1A9) is one of the most important UGT isoforms, and plays an important role in the metabolic elimination of therap......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 161 ()
The cynomolgus monkey is a nonhuman primate that is often used for pharmacokinetic and toxicokinetic studies of new chemical entities. Species differe......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 162 ()
The potential therapeutic and diagnostic applications of oligonucleotides have attracted great attention. However, natural antisense oligonucleotides ......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 164 ()
ZCY-15, N-(3,5-dimethyladamatan-1-yl)-N-(3-methylphenyl) urea, is a candidate compound synthesized from the memantine structure and has been shown to ......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 161 ()
MicroRNA185 (miR185), an endogenous noncoding RNA with 23 nucleotides, is one of key posttranscriptional modulators of cholesterol metabolism in hepat......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 162 ()
A new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a respiratory infection out broke in December 2019 in Wuhan, Hubei province, China......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 161 ()
Hyaluronan (HA) is a negatively charged linear polysaccharide that can interact with cluster determinant 44 (CD44) overexpressed cancers. However, HA ......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 162 ()
Alflutinib (AST2818) is a newly developed third-generation EGFR tyrosine kinase inhibitor for the treatment of lung cancer patients with T790M-resista......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 163 ()
Estriol can be used to treat radiation-induced leukopenia by increasing peripheral blood leukocytes and therefore it plays an important role in radiat......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 163 ()
Ceftazidime is a third-generation cephalosporin with high activity against many pathogens. But the ambiguity and diversity of the dosing regimens in n......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 162 ()
This work aims to synthesize two novel 1-MT (1-Methyl-DL-tryptophan) grafted CMCS (carboxymethyl chitosan) polymer prodrugs CMCS-amido-1-MT and CMCS-e......
期刊： EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 162 ()
Biapenem is a carbapenem antibiotic. It is excreted predominantly through the kidney as unchanged forms. However, the molecular mechanism of renal exc......
