筛选条件 共查询到194条结果
排序方式
MiR-1 is a critical regulator of chondrocyte proliferation and hypertrophy by inhibiting Indian hedgehog pathway during postnatal endochondral ossification in miR-1 overexpression transgenic mice

期刊: BONE, 2022; 165 ()

Endochondral bone formation from the growth plate plays a critical role in vertebrate limb development and skeletal homeostasis. Although miR-1 is mai......

JIF:4.047

N6-Methyladenosine-induced miR-143-3p promotes intervertebral disc degeneration by regulating SOX5

期刊: BONE, 2022; 163 ()

Intervertebral disc degeneration is the basic cause of lumbocrural pain, which not only causes pain and but also serious economic burdens on patients.......

JIF:4.047

mTORC1 coordinates NF-cB signaling pathway to promote chondrogenic differentiation of tendon cells in heterotopic ossification

期刊: BONE, 2022; 163 ()

Heterotopic ossification (HO) is a pathological bone formation based on endochondral ossification distinguished by ossification within muscles, tendon......

JIF:4.047

MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway

期刊: BONE, 2022; 154 ()

Rationale: The migration of osteoblastic cells to bone formation surface is an essential step for bone development and growth. However, whether the mi......

JIF:4.047

Impairment in activities of daily living and cognitive decline mediate the association between depressive symptoms and incident hip fractures in Chinese older adults

期刊: BONE, 2022; 159 ()

Background: The presence of depressive symptoms is associated with increasing risks of hip fractures (HFs). However, few studies investigated the long......

JIF:4.047

Coupling induction of osteogenesis and type H vessels by pulsed electromagnetic fields in ovariectomy-induced osteoporosis in mice

期刊: BONE, 2022; 154 ()

The growth of blood vessels and osteogenesis are coupled in bone tissue. A specialized subset of CD31(hi)Endomucinhi (CD31(hi)Emcn(hi)) vascular endot......

JIF:4.047

Glucocorticoid caused lactic acid accumulation and damage in human chondrocytes via ROS-mediated inhibition of Monocarboxylate Transporter 4

期刊: BONE, 2022; 155 ()

Osteoarthritis (OA) is a common joint disease lacking effective treatments. Dexamethasone (Dex) is often used to relieve joint pain. However, the adve......

JIF:4.047

An automatic measurement system of distal femur morphological parameters using 3D slicer software

期刊: BONE, 2022; 156 ()

In the field of joint surgery, the computer-aided design of knee prostheses suitable for the Chinese population requires a large quantity of anatomica......

JIF:4.047

Attenuation of cartilage pathogenesis in osteoarthritis by blocking the phosphorylation of tyrosine kinase Fyn to beta-catenin, AZD0530

期刊: BONE, 2022; 154 ()

Objective: To observe the effect of AZD0530 on the progression of knee OA after blocking beta-catenin phosphorylation and then dormancy of the Wnt/bet......

JIF:4.047

Mechanical stress reduces secreted frizzled-related protein expression and promotes temporomandibular joint osteoarthritis via Wnt/beta-catenin signaling

期刊: BONE, 2022; 161 ()

Aims: Mechanical stress overload in the temporomandibular joint (TMJ) is an important cause of TMJ osteoarthritis (TMJOA). Whether secreted frizzled-r......

JIF:4.047

PTX3 promotes osteogenic differentiation by triggering HA/CD44/FAK/AKT positive feedback loop in an inflammatory environment

期刊: BONE, 2022; 154 ()

The treatment of periodontitis-induced alveolar bone defects remains a clinical challenge. The secreted protein pentraxin 3 (PTX3) protects tissue dur......

JIF:4.047

Hip fractures risks in edoxaban versus warfarin users: A propensity score-matched population-based cohort study with competing risk analyses

期刊: BONE, 2022; 156 ()

Objective: The three direct oral anticoagulants (DOAC), rivaroxaban, apixaban and dabigatran have been associated with lower risks of fractures compar......

JIF:4.047

RANKL inhibition halts lesion progression and promotes bone remineralization in mice with fibrous dysplasia

期刊: BONE, 2022; 156 ()

Fibrous dysplasia (FD) is a rare bone disease caused by GNAS mutation in skeletal stem cells, typically originating from and worsening in childhood. T......

JIF:4.047

Lactate inhibits osteogenic differentiation of human periodontal ligament stem cells via autophagy through the MCT1-mTOR signaling pathway

期刊: BONE, 2022; 162 ()

Background: Periodontal ligament stem cells (PDLSCs) play a crucial role in periodontal bone regeneration. Lactate used to be considered a waste produ......

JIF:4.047

Intra-articular injection of a novel Wnt pathway inhibitor, SM04690, upregulates Wnt16 expression and reduces disease progression in temporomandibular joint osteoarthritis

期刊: BONE, 2022; 158 ()

Abnormal Wnt signaling has been shown to be involved in the pathogenesis of temporomandibular joint osteoarthritis (TMJOA). Recent studies demonstrate......

JIF:4.047

共194条页码: 1/13页15条/页