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The Raphe Dopamine System: Roles in Salience Encoding, Memory Expression, and Addiction

期刊: TRENDS IN NEUROSCIENCES, 2021; 44 (5)

Dopamine (DA) neurons of the dorsal raphe nucleus (DRN) were traditionally viewed as an extension of the ventral tegmental area (VTA) DA population. W......

Drosophila Mechanosensory Transduction

期刊: TRENDS IN NEUROSCIENCES, 2021; 44 (4)

Mechanosensation in Drosophila relies on sensory neurons transducing mechanical stimuli into ionic currents. The molecular mechanisms of this transduc......

The calcium-dependent protease calpain in neuronal remodeling and neurodegeneration

期刊: TRENDS IN NEUROSCIENCES, 2021; 44 (9)

Calpains are evolutionarily conserved and widely expressed Ca2+-activated cysteine proteases that act at neutral pH. The activity of calpains is tight......

Stopping the Clock on Seizures

期刊: TRENDS IN NEUROSCIENCES, 2021; 44 (6)

A recent paper by Zhang et al. shows that REV-ERB alpha, a negative regulator of the circadian molecu-lar clock, is pro-convulsant through its action ......

Drosophila Mechanosensory Transduction

期刊: TRENDS IN NEUROSCIENCES, 2020; 44 (4)

Mechanosensation in Drosophila relies on sensory neurons transducing mechanical stimuli into ionic currents. The molecular mechanisms of this transduc......

RNA N-6-Methyladenosine and the Regulation of RNA Localization and Function in the Brain

期刊: TRENDS IN NEUROSCIENCES, 2020; 43 (12)

A major challenge in neurobiology in the 21st century is to understand how the brain adapts with experience. Activity-dependent gene expression is int......

One or Two Ca2+ Stores in the Neuronal Endoplasmic Reticulum?

期刊: TRENDS IN NEUROSCIENCES, 2019; 42 (11)

It is generally accepted that the endoplasmic reticulum (ER) has one continuous lumen and operates as one uni-fied Ca2+ store, but new data from Chen-......

JIF:12.31

Lateral Habenular Burst Firing as a Target of the Rapid Antidepressant Effects of Ketamine

期刊: TRENDS IN NEUROSCIENCES, 2019; 42 (3)

The revolutionary discovery of the rapid antidepressant ketamine has been a milestone in psychiatry field in the last half century. Unlike conventiona......

JIF:12.31

Astroglia-Derived ATP Modulates CNS Neuronal Circuits

期刊: TRENDS IN NEUROSCIENCES, 2019; 42 (12)

It is broadly recognized that ATP not only supports energy storage within cells but is also a transmitter/signaling molecule that serves intercellular......

JIF:12.31

Flexible Roles for Proteoglycan Sulfation and Receptor Signaling

期刊: TRENDS IN NEUROSCIENCES, 2018; 41 (1)

Proteoglycans (PGs) in the extracellular matrix (ECM) play vital roles in axon growth and navigation, plasticity, and regeneration of injured neurons.......

JIF:12.31

Retinal Cell Fate Specification

期刊: TRENDS IN NEUROSCIENCES, 2018; 41 (4)

How are different neural cell types generated from progenitor cells? In 1990, Turner et al. used new lineage tracing techniques to show that different......

JIF:12.31

Neural Cell Adhesion Molecules of the Immunoglobulin Superfamily Regulate Synapse Formation, Maintenance, and Function

期刊: TRENDS IN NEUROSCIENCES, 2017; 40 (5)

Immunoglobulin superfamily adhesion molecules are among the most abundant proteins in vertebrate and invertebrate nervous systems. Prominent family me......

JIF:11.44

Developmental Connectomics from Infancy through Early Childhood

期刊: TRENDS IN NEUROSCIENCES, 2017; 40 (8)

The human brain undergoes rapid growth in both structure and function from infancy through early childhood, and this significantly influences cognitiv......

JIF:11.44

Brain cell type-specific cholesterol metabolism and implications for learning and memory

期刊: TRENDS IN NEUROSCIENCES, 2022; 45 (5)

Cholesterol homeostasis is vital for brain function. Brain cholesterol is locally synthesized, with varying synthesis capacities across different cell......

JIF:7.801

Spinal ascending pathways for somatosensory information processing

期刊: TRENDS IN NEUROSCIENCES, 2022; 45 (8)

The somatosensory system processes diverse types of information including mechanical, thermal, and chemical signals. It has an essential role in senso......

JIF:7.801

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