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Identification and characterization of the Cucurbitacins, a novel class of small-molecule inhibitors of Tropomyosin receptor kinase a

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 (1)

Background NGF-TrkA is well known to play a key role in propagating and sustaining pruritogenic signals, which form the pathology of chronic pruritus.......

JIF:2.48

Treatment satisfaction in Chinese medicine outpatient care: a comparison of patients' and doctors' views

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 (1)

Background Both doctors' and patients' opinions are important in the process of treatment and healthcare of Chinese medicine. This study is to compare......

JIF:2.48

Placebo design in WHO-registered trials of Chinese herbal medicine need improvements

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 (1)

BackgroundPhysical identical and pharmacological inert are the basic requirements for placebo design, which are essential in clinical trials to evalua......

JIF:2.48

Characterization, evaluation of nutritional parameters of Radix isatidis protein and its antioxidant activity in D-galactose induced ageing mice

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 (1)

BackgroundRadix isatidis (Isatis indigotica Fort.) is an ancient medicinal herb, which has been applied to the prevention and treatment of influenza v......

JIF:2.48

The traditional Chinese formulae Ling-gui-zhu-gan decoction alleviated non-alcoholic fatty liver disease via inhibiting PPP1R3C mediated molecules

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

BackgroundLing-gui-zhu-gan decoction (LGZG), a classic traditional Chinese medicine formula, has been confirmed to be effective in improving steatosis......

JIF:2.48

Danggui Buxue Tang, an ancient Chinese herbal decoction, protects -amyloid-induced cell death in cultured cortical neurons

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

BackgroundDanggui Buxue Tang (DBT) is a historical Chinese herbal decoction, and which has more than 800years of applications. This herbal decoction s......

JIF:2.48

Coreopsis tinctoria Nutt ameliorates high glucose-induced renal fibrosis and inflammation via the TGF-1/SMADS/AMPK/NF-B pathways

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

BackgroundCoreopsis tinctoria Nutt is an ethnomedicine widely used in Xinjiang, China. It is consumed as a herbal tea by local Uyghur people to treat ......

JIF:2.48

Twelve Chinese herbal preparations for the treatment of depression or depressive symptoms in cancer patients: a systematic review and meta-analysis of randomized controlled trials

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

BackgroundPatients with cancer are vulnerable to depression or other depressive conditions. The aim of this paper was to evaluate the efficacy and saf......

JIF:2.48

Effect of Osteoking on the osteogenic and adipogenic differentiation potential of rat bone marrow mesenchymal stem cells in vitro

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

BackgroundBone damage is a condition that affects the quality of life of patients. Mesenchymal stem cells (MSCs) are important for bone repair. Osteok......

JIF:2.48

Wu-Mei-wan protects pancreatic cells by inhibiting NLRP3 Inflammasome activation in diabetic mice

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

BackgroundWu-Mei-Wan (WMW) is a traditional Chinese herbal formulation that is clinically prescribed to treat diabetes mellitus in China. WMW has been......

JIF:2.48

2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

Background: Signal transducer and activator of transcription 3 (STAT3) is an oncogene constitutively activated in hepatocellular carcinoma (HCC) cells......

JIF:2.48

Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 (1)

Background The aim of the present study was to examine the effects of the Bolbostemma paniculatum (Maxim.) Franquet (BP) active compound, BP total sap......

JIF:2.48

Effects of Radix Linderae extracts on a mouse model of diabetic bladder dysfunction in later decompensated phase

期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019; 19 ()

BackgroundThis study aimed to elucidate the effects and mechanisms of Radix Linderae (RL) extracts on a mouse model of diabetic bladder dysfunction (D......

JIF:2.48

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