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A Five-mRNA Expression Signature to Predict Survival in Oral Squamous Cell Carcinoma by Integrated Bioinformatic Analyses

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (8)

Objectives: This study was designed to identify a messenger RNA (mRNA) expression signature to predict survival in patients with oral squamous cell ca......

MAFK Polymorphisms Located in 3 '-UTR are Associated with Severity of Atrophy and CDKN2A Methylation Status in the Gastric Mucosa

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (4)

Objective: This study aimed to clarify the association of MAFK polymorphisms (rs4268033, rs3735656, and rs10226620) with the degree of gastric mucosal......

Construction of Competing Endogenous RNA Networks Incorporating Transcription Factors to Reveal Differences in Granulosa Cells from Patients with Endometriosis

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (7)

Purpose: This study aimed to reveal the molecular differences in granulosa cells (GCs) from patients with endometriosis (EM). Methods: RNA sequencing ......

Evaluation of the Genetic Association and Methylation of Immune Response Pathway Genes with the Risk of Chronic Periodontitis in the Uighur Population

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (5)

Aim: The aim of this study was to explore the possible associations between single nucleotide polymorphisms (SNPs) and DNA methylation levels of seven......

miR-1 Targeted Downregulation of Bcl-2 Increases Chemosensitivity of Lung Cancer Cells

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (8)

Objective: To investigate the expression of B cell lymphoma-2 (Bcl-2) in lung cancer cells and the effect of the miR-1/Bcl-2 axis on the chemosensitiv......

Whole-Exome Sequencing Identified DLG1 as a Candidate Gene for Familial Exudative Vitreoretinopathy

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (5)

Purpose: Familial exudative vitreoretinopathy (FEVR) is a blinding retinal vascular disease. Clinically, FEVR is characterized by incomplete vasculari......

Correlation Between Polymorphisms of the SIRT1 Gene microRNA Target Sites and Diabetic Nephropathy

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (6)

Objective: To study the correlations between the genotypic and allelic frequencies of the Sirtuin 1 (SIRT1) gene rs182180876, rs4746720, and rs2234975......

The CYP19A1 rs700519 Polymorphism and Breast Cancer Susceptibility in China: A Case-Control Study and Updated Meta-Analysis

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (7)

Objective: Breast cancer (BC), the most prevalent cancer in women, has been associated with several genetic factors, including the CYP19A1 rs700519 po......

Association Study of Mitochondrial DNA Haplogroup D and C5178A Polymorphisms with Chronic Kidney Disease

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (8)

Objective: To explore the associations of common mitochondrial DNA polymorphisms with chronic kidney disease (CKD). Methods: Data from 286 longevous i......

Screening of Potential Key Genes Related to Tubal Factor Infertility Based on Competitive Endogenous RNA Network

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (5)

Background: The molecular biological mechanism of tubal factor infertility (TFI) is still unclear. Long noncoding RNAs (lncRNAs) are considered a majo......

The MMP-1 Gene rs1799750 Polymorphism Is Associated with Breast Cancer Risk

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (7)

Numerous studies investigating an association between the matrix metalloproteinase-1 (MMP-1) gene rs1799750 polymorphism and breast cancer (BC) risk h......

Significance of TP53 Mutation in Cellular Process and Disease Progression in Lung Adenocarcinoma

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (5)

Introduction: TP53 (tumor protein p53) is one of the most commonly mutanted genes in lung adenocarcinoma (LUAD). Materials and Methods: In this study,......

Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (5)

Objective: This study investigated the association of the TaqI (rs731236 T>C) polymorphism in the VDR gene with dental caries. Methods: A comprehen......

LncRNA-HEIH is a Novel Diagnostic and Predictive Biomarker in Gastric Cancer

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (4)

Background: Gastric cancer (GC) is associated with a high mortality rate. Long noncoding RNA (lncRNA)-high expressed in hepatocellular carcinoma (HEIH......

Association Between TPM1 Gene Polymorphisms and Idiopathic Congenital Talipes Equinovarus Risk in a Chinese Population

期刊: GENETIC TESTING AND MOLECULAR BIOMARKERS, 2021; 25 (5)

Background: Idiopathic congenital talipes equinovarus (ICTEV) is one of the most common congenital deformities of children, and dysplasia of the stria......

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