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Prognostic and predictive significance of the tumor microenvironment in hepatocellular carcinoma

期刊: CANCER BIOMARKERS, 2021; 32 (1)

BACKGROUND: Identification of molecular markers that reflect the characteristics of the tumor microenvironment (TME) may be beneficial to predict the ......

Salivary KLK5 and uPA are potential biomarkers for malignant transformation of OLK and OLP

期刊: CANCER BIOMARKERS, 2021; 31 (4)

BACKGROUND: Oral squamous cell carcinoma (OSCC) usually originates from oral potentially malignant disorders (OPMD), such as oral leukoplakia (OLK) an......

Three plasma-based microRNAs as potent diagnostic biomarkers for endometrial cancer

期刊: CANCER BIOMARKERS, 2021; 31 (2)

BACKGROUND: MicroRNAs (miRNAs), with noticeable stability and unique expression pattern in plasma of patients with various diseases, are powerful non-......

High expression of ISG20 predicts a poor prognosis in acute myeloid leukemia

期刊: CANCER BIOMARKERS, 2021; 31 (3)

BACKGROUND: Acute myeloid leukemia (AML) is one of the most malignant hematopoietic system diseases. Interferon stimulated exonuclease gene 20 (ISG20)......

FAM196B promotes proliferation and migration via regulating epithelial-mesenchymal transition in esophageal cancer

期刊: CANCER BIOMARKERS, 2021; 31 (1)

BACKGROUND: EC (esophageal cancer) is a common cancer among people in the world. The molecular mechanism of FAM196B (family with sequence similarity 1......

The alpha 2 delta 1 subunit of the voltage-gated calcium channel acts as a potential candidate for breast cancer tumor initial cells biomarker

期刊: CANCER BIOMARKERS, 2021; 31 (3)

BACKGROUND: The voltage-gated calcium channel subunit alpha 2 delta 1 (alpha 2 gamma 1) is a functional tumor initial cells (TICs) marker for some sol......

The relationship between LncRNAs and lung adenocarcinoma as well as their ceRNA network

期刊: CANCER BIOMARKERS, 2021; 31 (2)

BACKGROUND: More and more studies have shown that long non-coding RNA (LncRNA) as a competing endogenous RNA (ceRNA) plays an important role in lung c......

Prognostic role of pretreatment lung immune prognostic index in extensive-stage small-cell lung cancer treated with platinum plus etoposide chemotherapy

期刊: CANCER BIOMARKERS, 2021; 31 (2)

BACKGROUND: To investigate the prognostic role of lung immune prognostic index (LIPI) in extensive-stage small-cell lung cancer (ES-SCLC) patients tre......

Diagnostic value of oncofetal miRNAs in cancers: A comprehensive analysis of circulating miRNAs in pan-cancers and UCB

期刊: CANCER BIOMARKERS, 2021; 32 (1)

BACKGROUND: Circulating miRNAs are promising biomarkers for detection of various cancers. As a "developmental" disorder, cancer showed great similarit......

LncRNA testis-specific transcript, Y-linked 15 (TTTY15) promotes proliferation, migration and invasion of colorectal cancer cells via regulating miR-29a-3p/DVL3 axis

期刊: CANCER BIOMARKERS, 2021; 31 (1)

BACKGROUND: Long non-coding RNA testis-specific transcript, Y-linked 15 (TTTY15) is oncogenic in prostate cancer, however its expression and function ......

Genetic variants in STAT4 and their interactions with environmental factors for the incidence of hepatocellular carcinoma

期刊: CANCER BIOMARKERS, 2021; 32 (1)

BACKGROUND: A recent genome-wide association study (GWAS) has posed STAT4 as a promising susceptibility gene for hepatocellular carcinoma (HCC). Howev......

RUNX2 promotes malignant progression in gastric cancer by regulating COL1A1

期刊: CANCER BIOMARKERS, 2021; 31 (3)

BACKGROUND: Runt-related transcription factor 2 (RUNX2) is an important gene that has been implicated in the progression of human cancer. Aberrant exp......

Homeobox-A13 acts as a functional prognostic and diagnostic biomarker via regulating P53 and Wnt signaling pathways in lung cancer

期刊: CANCER BIOMARKERS, 2021; 31 (3)

BACKGROUND: The prognosis of lung cancer patients is poor without useful prognostic and diagnostic biomarker. To search for novel prognostic and diagn......

The expression and diagnostic value of serum levels of EphA2 and VEGF-A in patients with colorectal cancer

期刊: CANCER BIOMARKERS, 2021; 31 (4)

BACKGROUND: Several molecules are highly expressed in the serum of cancer patients, and can be used as serological markers. This approach has become o......

Significant difference of c-type lectin-like receptor 2 between colorectal cancer and polyp subgroups

期刊: CANCER BIOMARKERS, 2021; 31 (2)

BACKGROUND: Platelets play a key role in tumor progression and metastasis. C-type lectin-like receptor 2 (CLEC-2) is the receptor expressed on platele......

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