筛选条件 共查询到365条结果
排序方式
The PPAR-gamma/SFRP5/Wnt/beta-catenin signal axis regulates the dexamethasone-induced osteoporosis

期刊: CYTOKINE, 2021; 143 ()

Background: The inhibition of glucocorticoid (GC) on osteoblastic differentiation of bone marrow stromal stem cells (BMSC) is an important pathway for......

The hidden secrets of soluble RANKL in bone biology

期刊: CYTOKINE, 2021; 144 ()

The discovery of cytokine tumor necrosis factor (TNF) in the 20th century revealed numerous secrets about organ development. In particular, the functi......

Extensive cytokine analysis in synovial fluid of osteoarthritis patients

期刊: CYTOKINE, 2021; 143 ()

Objective: Osteoarthritis (OA) is a joint disease characterized by articular cartilage loss and afflicts many people worldwide. However, diagnostic me......

MIF-mediated NF-B-K signaling pathway regulates the pathogenesis of polycystic ovary syndrome in rats

期刊: CYTOKINE, 2021; 146 ()

Polycystic ovary syndrome (PCOS) resulting from abnormal glucose metabolism is a relatively common and complex endocrine disorder among women in their......

Lipid-injured hepatocytes release sOPN to improve macrophage migration via CD44 engagement and pFak-NF kappa B signaling

期刊: CYTOKINE, 2021; 142 ()

Background: The key characteristics in the pathogenesis of nonalcoholic steatohepatitis (NASH) are hepatic lipotoxicity, inflammatory cell infiltratio......

Knockdown of lncRNA PVT1 attenuated macrophage M1 polarization and relieved sepsis induced myocardial injury via miR-29a/HMGB1 axis

期刊: CYTOKINE, 2021; 143 ()

Background: LncRNA PVT1 was reported to be elevated in septic myocardial tissue. The underlying mechanism by which PVT1 aggravated sepsis induced myoc......

Interleukin-36 gamma aggravates macrophage foam cell formation and atherosclerosis progression in ApoE knockout mice

期刊: CYTOKINE, 2021; 146 ()

Atherosclerosis-related cardiovascular diseases are the leading cause of mortality worldwide. Macrophagederived foam cell formation is a critical earl......

Promoting effects of MiR-135b on human multiple myeloma cells via regulation of the Wnt/13-catenin/Versican signaling pathway

期刊: CYTOKINE, 2021; 142 ()

MicroRNA (MiR)-135b and its mediated Wnt/13-catenin signaling pathway are involved in human malignancies. However, their roles in multiple myeloma (MM......

Perspectives on anti-IL-1 inhibitors as potential therapeutic interventions for severe COVID-19

期刊: CYTOKINE, 2021; 143 ()

The overproduction of proinflammatory cytokines, resulting in what has been described as a cytokine storm or cytokine release syndrome (CRS), may be t......

Lactobacillus johnsonii activates porcine monocyte derived dendritic cells maturation to modulate Th cellular immune response

期刊: CYTOKINE, 2021; 144 ()

Lactobacilli are abundant in the intestinal tract where they constantly regulate immune system via interacting with a great diversity of immune cells,......

H2S inhibits atrial fibrillation-induced atrial fibrosis through miR-133a/CTGF axis

期刊: CYTOKINE, 2021; 146 ()

Aim: Atrial fibrillation (AF) is a common clinical arrhythmia and can cause a variety of complications. To study the therapeutic effect of H2S in atri......

Serum IP-10 and IL-7 levels are associated with disease severity of coronavirus disease 2019

期刊: CYTOKINE, 2021; 142 ()

We quantified the serum levels of 34 cytokines/chemokines in 30 patients with SARS-CoV-2 infection. Elevated levels of IP-10 and IL-7 were detected in......

Interleukin-6 participates in human pancreatic stellate cell activation and collagen I production via TGF-beta 1/Smad pathway

期刊: CYTOKINE, 2021; 143 ()

Pancreatic stellate cells (PSCs) play a key role in fibrogenesis during alcoholic chronic pancreatitis (ACP). Transforming growth factor-beta 1 (TGF-b......

The dual role of complement in cancers, from destroying tumors to promoting tumor development

期刊: CYTOKINE, 2021; 143 ()

Complement is an important branch of innate immunity; however, its biological significance goes far beyond the scope of simple nonspecific defense and......

Interferon-gamma inhibits retinal neovascularization in a mouse model of ischemic retinopathy

期刊: CYTOKINE, 2021; 143 ()

Interferon-gamma (IFNG) is one of the key cytokines that regulates both innate and adaptive immune responses in the body. However, the role of IFNG in......

共365条页码: 1/25页15条/页