Aims Diabetic nephropathy (DN) is a leading cause of end-stage renal disease. BASP1 (brain acid-soluble protein) is up-regulated in podocyte-specific ......
期刊： ACTA PHYSIOLOGICA, 2021; 231 (4)
Aim: Epigallocatechin-3-gallate (EGCG), the major polyphenol found in green tea, exerts multiple protective effects against cardiovascular diseases, i......
期刊： ACTA PHYSIOLOGICA, 2021; 231 (4)
Aim: cAMP typically signals downstream of G(s)-coupled receptors and regulates numerous cell functions. In beta-cells, cAMP amplifies Ca2+-triggered e......
期刊： ACTA PHYSIOLOGICA, 2021; 231 (4)
Aim Oxytocin plays an important role in social recognition in rodents, which is mediated predominantly by the olfactory system. Although oxytocin modu......
期刊： ACTA PHYSIOLOGICA, 2020; 230 (4)
Aim MRP2 is an intestinal ABC transporter that prevents the absorption of dietary xenobiotics. The aims of this work were: (1) to evaluate whether a s......
期刊： ACTA PHYSIOLOGICA, 2020; 230 (2)
Aim FMS-like receptor tyrosine kinase 3 (Flt3) has been reported to be increased in cardiomyocytes responding to ischaemic stress. This study was to d......
期刊： ACTA PHYSIOLOGICA, 2020; 230 (1)
Aim Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in the heart, but its function there is unclear. CFTR regulates an ATP rel......
期刊： ACTA PHYSIOLOGICA, 2020; 230 (2)
Aim SLC26A3 (DRA) mediates the absorption of luminal Cl(-)in exchange for HCO(3)(-)in the distal intestine. Its expression is lost in congenital chlor......
期刊： ACTA PHYSIOLOGICA, 2020; 230 (3)
Aim The imbalance of T helper (Th) 17/T regulatory (Treg) is involved in chronic heart failure (HF). The enzyme lysyl oxidase (LOX) contributes to myo......
期刊： ACTA PHYSIOLOGICA, 2020; 229 (4)
Reactive oxygen species (ROS) are produced by the aerobic metabolism. The imbalance between production of ROS and antioxidant defence in any cell comp......
期刊： ACTA PHYSIOLOGICA, 2020; 230 (1)
Aim Adipose-derived stem cells (ASCs) therapies are emerging as a promising approach to therapeutic angiogenesis. Therapeutic persistence and reduced ......
Aim Dilated cardiomyopathy (DCM) is characterised by left ventricular dilation and associated with systolic dysfunction. Recent evidence has reported ......
期刊： ACTA PHYSIOLOGICA, 2019; 225 (1)
Aim Loss-of-function mutation of Akt3 in humans has been associated with microcephaly and cognitive defects. Two Akt isoforms, Akt1 and Akt3, are high......
