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Risk of osteonecrosis in systemic lupus erythematosus: An 11-year Chinese single-center cohort study

期刊: LUPUS, 2021; 30 (9)

Objective: Osteonecrosis (ON), which can lead to physical disability, is a common complication of systemic lupus erythematosus (SLE). The purpose of t......

The high expression of miR-564 in patients with systemic lupus erythematosus promotes differentiation and maturation of DC cells by negatively regulating TP53 expression in vitro

期刊: LUPUS, 2021; 30 (9)

Background miRNA is involved in the occurrence and progression of systemic lupus erythematosus (SLE), but the regulatory effect of miRNA on dendritic ......

Age differences in secular trends in black-white disparities in mortality from systemic lupus erythematosus among women in the United States from 1988 to 2017

期刊: LUPUS, 2021; 30 (5)

Objective To examine the age differences in secular trends in black-white disparities in mortality from systemic lupus erythematosus (SLE) among women......

Resolution of huge thrombi in bilateral ventricles caused by severe lupus cardiomyopathy

期刊: LUPUS, 2021; 30 (5)

Ventricular thrombus is an uncommon, severe condition with high morbidity and mortality. Simultaneous left and right ventricular thrombi caused by lup......

Association between alcohol intake and the risk of systemic lupus erythematosus: A systematic review and meta-analysis

期刊: LUPUS, 2021; 30 (5)

Objectives Previous studies have reported inconsistent results on the relationship between alcohol intake and the risk of systemic lupus erythematosus......

Hydroxychloroquine prophylaxis for preeclampsia, hypertension and prematurity in pregnant patients with systemic lupus erythematosus: A meta-analysis

期刊: LUPUS, 2021; 30 (7)

Objectives This meta-analysis aimed to evaluate the effectiveness of HCQ in improving the maternal and fetal outcomes in pregnancies with SLE. Methods......

Clinico-pathological associations of serum VCAM-1 and ICAM-1 levels in patients with lupus nephritis

期刊: LUPUS, 2021; 30 (7)

Objective We investigated the clinico-pathological associations of serum VCAM-1 and ICAM-1 levels in patients with biopsy-proven Class III/IV +/- V lu......

Uncoupled bone remodeling is characteristic of bone damage in premenopausal women with new-onset systemic lupus erythematosus

期刊: LUPUS, 2021; 30 (7)

Objective To investigate the mechanism underlying systemic lupus erythematosus (SLE)-related bone loss by evaluating the bone mineral density (BMD) an......

Association of PER2 gene single nucleotide polymorphisms with genetic susceptibility to systemic lupus erythematosus

期刊: LUPUS, 2021; 30 (5)

The circadian clock plays a crucial role in the progress of systemic lupus erythematosus (SLE). In this study, we performed a case-control study to ex......

Potential genetic basis of B cell hyperactivation in murine lupus models

期刊: LUPUS, 2021; 30 (9)

Background Lupus B cells not only produce autoantibodies against nuclear antigens but also provide co-stimulation to T cells. However, there is still ......

The changes in bone turnover markers of female systemic lupus erythematousus patients without glucocorticoid

期刊: LUPUS, 2021; 30 (6)

Objectives SLE is a chronic autoimmune disease, which can affect the level of bone metabolism and increase the risk of osteoporosis and fracture. The ......

Acute pericardial tamponade: The initial manifestation of systemic lupus erythematosus with Graves' hyperthyroidism

期刊: LUPUS, 2021; 30 (7)

Acute pericardial tamponade, which can cause obstructive shock, is a serious life-threatening medical emergency that can be readily reversed by timely......

Bioinformatic analysis of key biomarkers and immune filtration of skin biopsy in discoid lupus erythematosus

期刊: LUPUS, 2021; 30 (5)

Objective Discoid lupus erythematosus (DLE) is the most common category of chronic cutaneous lupus erythematosus, where the pathological process is pr......

Distribution of IgG subclass anti-nuclear antibodies (ANAs) in systemic lupus erythematosus

期刊: LUPUS, 2021; 30 (6)

Objectives Our study purpose was to detect the distribution of anti-nuclear antibody (ANA) IgG subclasses in patients with systemic lupus erythematosu......

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