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Regorafenib Induces the Apoptosis of Gastrointestinal Cancer-Associated Fibroblasts by Inhibiting AKT Phosphorylation

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14)

Cancer-associated fibroblasts (CAFs) are a key component of the tumor microenvironment and are essential for tumorigenesis and development. Regorafeni......

JIF:2.983

Research Progress of Totipotent Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14)

Totipotent stem cells (TSCs), can develop into complete organisms, are used in biological fields such as regenerative medicine, mammalian breeding, an......

JIF:2.983

MicroRNA-7a2 is Required for the Development of Pituitary Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14)

The pituitary gland is inhabited by a subpopulation of SOX2(+) stem cells. However, the regulatory mechanisms underlying pituitary stem cell developme......

JIF:2.983

An Updated View on Temporomandibular Joint Degeneration: Insights from the Cell Subsets of Mandibular Condylar Cartilage

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (15-16)

The high prevalence of temporomandibular joint osteoarthritis (TMJOA), which causes joint dysfunction, indicates the need for more effective methods f......

JIF:2.983

Methodological Quality and Risk of Bias of Systematic Reviews and Meta-Analyses on Stem Cells for Knee Osteoarthritis: A Cross-Sectional Survey

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (15-16)

Clinical guidelines need high-quality studies to support clinical decision making, in which the evidence often was collected from systematic reviews (......

JIF:2.983

miR-1275 Inhibits Human Omental Adipose-Derived Stem Cells Differentiation Toward the Beige Phenotype via PRDM16

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (23-24)

Beige adipocytes have recently attracted attention for their potential as new therapeutic targets in the management of obesity and related metabolic d......

JIF:2.983

Distinctive Clinical and Pathologic Features of Immature Teratomas Arising from Induced Pluripotent Stem Cell-Derived Beta Cell Injection in a Diabetes Patient

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (5-6)

Induced pluripotent stem cells (iPSCs) are a new potential cure for diabetes, characterized by a capacity for self-renewal and differentiation to panc......

JIF:2.983

Proteomic Analysis of Retinal Conditioned Medium: The Effect on Early Differentiation of Embryonic Stem Cells into Retina

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (21-22)

Stem cell replacement therapy has emerged as one of the most promising treatment options for retinal degenerative diseases, which are the main causes ......

JIF:2.983

Cytoplasm or Supernatant: Where Is the Treasury of the Bioactive Antiaging Factor from Mesenchymal Stem Cells?

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (17-18)

Cell-free compounds of mesenchymal stem cells (MSCs) could be a safer and cheaper substitution for MSC transplantation and have gained substantial res......

JIF:2.983

Micro-Injury Induces Hair Regeneration and Vitiligo Repigmentation Through Wnt/beta-Catenin Pathway

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (5-6)

Extrinsic injury can evoke intrinsic stimulation and subsequently initiate the physiological repair process. This study aims to investigate whether cl......

JIF:2.983

Downregulating MFN2 Promotes the Differentiation of Induced Pluripotent Stem Cells into Mesenchymal Stem Cells through the PI3K/Akt/GSK-3 beta/Wnt Signaling Pathway

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (7-8)

Understanding the mechanism of the differentiation of induced pluripotent stem cells (iPSCs) into mesenchymal stem cells (MSCs) and promoting the prod......

JIF:2.983

Human Neural Stem Cell Secretome Inhibits Lipopolysaccharide-Induced Neuroinflammation Through Modulating Microglia Polarization by Activating Peroxisome Proliferator-Activated Receptor Gamma

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14)

Neuroinflammation is one of the typical events in multiple neurodegenerative diseases, whereas microglia are the critical participants in the pathogen......

JIF:2.983

Genome-Wide CRISPR Screen Identifies Puf60 as a Novel Stemness Gene of Mouse Embryonic Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (5-6)

The mechanisms underlying self-renewal of embryonic stem cells (ESCs) hold great value in the clinical translation of stem cell biology and regenerati......

JIF:2.983

Bromodeoxyuridine Methodology for Labeling Renal Stem Cells During Kidney Development of Mice

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (7-8)

A continuous Bromodeoxyuridine (BrdU) labeling approach was used during the whole process of the mice kidney development to explore the best BrdU-labe......

JIF:2.983

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