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Dysregulated Expression Levels of Circular RNAs Serve as Prognostic and Clinicopathological Markers in Gastric Cancer: a Meta-Analysis

期刊: CLINICAL LABORATORY, 2021; 67 (4)

Background: Circular RNAs (circRNAs) are novel biomarkers that are widely investigated in various cancers. There is increasing evidence that the expre......

Plasma miR-1, but not Extracellular Vesicle miR-1, Functions as a Potential Biomarker for Colorectal Cancer Diagnosis

期刊: CLINICAL LABORATORY, 2021; 67 (1)

Background: miRNAs have been proved to function as diagnostic biomarkers. Extracellular vesicles (EVs) are carriers of miRNAs. This study aimed to inv......

Severely High Lactic Acid in Severe Pneumonia Patient: a Case Report

期刊: CLINICAL LABORATORY, 2021; 67 (3)

Background: Severe pneumonia (SP) is a clinically critical acute disease which has a higher mortality rate among infectious diseases. In this report, ......

Clinical Characteristics, Serological and Radiological Longitudinal Changes of Patients with COVID-19

期刊: CLINICAL LABORATORY, 2021; 67 (4)

Background: Since December 2019, an outbreak of coronavirus disease 2019 (COVID-19) began in Wuhan and rapidly spread globally. The speed and scope of......

Potential Biomarkers in Early Pregnancy for Predicting Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes

期刊: CLINICAL LABORATORY, 2021; 67 (8)

Background: Gestational diabetes mellitus (GDM) is typically diagnosed based on a 75-g oral glucose tolerance test conducted at 24 - 28 weeks of pregn......

Diagnostic Value of Exosomal miR-148a-3p in the Serum of Patients with Differentiated Thyroid Cancer

期刊: CLINICAL LABORATORY, 2021; 67 (2)

Background: The current study aims to evaluate the expression and diagnostic value of exosomal miR-148a-3p in the serum of DTC patients. Methods: Exos......

Diagnostic Role of Long Non-Coding RNAs in Breast Cancer: a Systematic Review and Meta-Analysis

期刊: CLINICAL LABORATORY, 2021; 67 (3)

Background: Recent research has suggested that long non-coding RNA (lncRNA) is involved in the tumorigenesis and development of breast cancer (BC). Th......

The Role of Cholinesterase in Differential Diagnosis between Gastric Cancer and Benign Gastric Diseases

期刊: CLINICAL LABORATORY, 2021; 67 (2)

Background: Gastric cancer is the fifth most common malignancy worldwide. In early stages, no obvious symptoms are usually observed in gastric cancer ......

Elevated Serum Myeloid-Related Protein (MRP) 8/14 in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

期刊: CLINICAL LABORATORY, 2021; 67 (2)

Background: The current study aims to evaluate the expression and clinical significance of myeloid-related protein (MRP) 8/14 in patients with acute e......

Homocystinuria in a Family with Novel Cystathionine Beta Synthase Gene Mutations

期刊: CLINICAL LABORATORY, 2021; 67 (2)

Background: Classic homocystinuria is caused by cystathionine beta synthase deficiency owing to genetic mutations. The most common symptoms are ectopi......

Hepatitis B Virus Affected Serum MicroRNA-203a Level in Hepatocellular Carcinoma

期刊: CLINICAL LABORATORY, 2021; 67 (3)

Background: MicroRNAs have been shown to play a critical role in early diagnosis of hepatocellular carcinoma. Nevertheless, microRNAs' functions in se......

Serum TBA and GCA Levels Across Pregnancy and the Gestational Age-Specific Reference Intervals for Pregnant Chinese

期刊: CLINICAL LABORATORY, 2021; 67 (6)

Background: Reference intervals of clinical laboratory indexes are the basis of interpretation of test results. While intrahepatic cholestasis of preg......

Acyl-Coenzyme A: Cholesterol Acyltransferase-1 is Related to Hyperlipidemia in Children with Nephrotic Syndrome

期刊: CLINICAL LABORATORY, 2021; 67 (5)

Background: Hyperlipidemia is one of the characteristics of nephrotic syndrome, and cellular lipid accumulation in the kidney can accelerate kidney di......

Increased ADAM12 Expression Predicts Poor Prognosis in Cervical Cancer Patients before General Anesthesia

期刊: CLINICAL LABORATORY, 2021; 67 (2)

Background: The current study aims to investigate the expression and diagnostic value of ADAM12 in patients with cervical cancer before general anesth......

Study on Laboratory Indicators Related to Lung Injury of Corona Virus Disease 2019

期刊: CLINICAL LABORATORY, 2021; 67 (1)

Background: Since December 2019, a series of pneumonia cases caused by COVID-19 emerged in Wuhan, Hubei Province, China. People are generally suscepti......

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