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Visible light-controlled carbon monoxide delivery combined with the inhibitory activity of histone deacetylases from a manganese complex for an enhanced antitumor therapy

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 216 ()

Multifunctional drugs with synergistic effects have been widely developed to enhance the treatment efficiency of various diseases, such as malignant t......

Ruthenium(II) 1,4,7-trithiacyclononane complexes of curcumin and bisdemethoxycurcumin: Synthesis, characterization, and biological activity

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 218 ()

Two cationic ruthenium(II) 1,4,7-trithiacyclononane ([9]aneS3) complexes of curcumin (curcH) and bisdemethoxycurcumin (bdcurcH), namely [Ru(curc)(dmso......

Carbon quantum dots modified Ag2S/CS nanocomposite as effective antibacterial agents

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 220 ()

The present study attempted to synthesize carbon quantum dots (CQDs) through Aldol polymerization reaction, wherein acetone was used as the carbon sou......

Anti-metastasis and anti-proliferation effect of mitochondria-accumulating ruthenium(II) complexes via redox homeostasis disturbance and energy depletion

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 217 ()

The antiproliferative activity of three cyclometalated Ru(II) complexes with the formula [Ru(bpy)(2)L]PF6, where bpy = 2,2'-bipyridine, Ru1: L1 = phen......

Synthesis, electrochemistry, DNA binding and in vitro cytotoxic activity of tripodal ferrocenyl bis-naphthalimide derivatives

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 219 ()

A series of tripodal ferrocenyl bis-naphthalimide derivatives were synthesized and characterized. All of the bisnaphthalimide derivatives exhibited go......

Diatom-like silica-protein nanocomposites for sustained drug delivery of ruthenium polypyridyl complexes

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 221 ()

Inspired by the unique glass cell wall of diatom, we design a new nanostructure of human serum albumin nanoparticle (HSANP) coated with silica (HSA/Si......

3D CoPt nanostructures hybridized with iridium complexes for multimodal imaging and combined photothermal-chemotherapy

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 219 ()

Combined photothermal-chemotherapy has shown great potential in improving the efficiency of tumor treatment. In this article, we have designed a new t......

Iridium(III)-BBIP complexes induce apoptosis via PI3K/AKT/mTOR pathway and inhibit A549 lung tumor growth in vivo

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 223 ()

The new ligand BBIP (BBIP = 2-(7-bromo-2H-benzo[d]imidazole-4-yl)-1H-imidazo[4,5-f][1,10]phenanthroline) with its iridium(III) complexes: [Ir(ppy)2(BB......

Design and application of nanoparticles as vaccine adjuvants against human corona virus infection

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 219 ()

In recent years, some viruses have caused a grave crisis to global public health, especially the human coronavirus. A truly effective vaccine is there......

Structural and functional characterization of complexes between heme and dimeric parallel G-quadruplex DNAs

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 216 ()

Heme has been receiving considerable interest as a prosthetic group of ribozymes and deoxyribozymes, because heme-bound nucleic acids exhibit peroxida......

BODIPY-based monofunctional Pt (II) complexes for specific photocytotoxicity against cancer cells

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 218 ()

Photodynamic therapy (PDT) has attracted extensive attention in cancer treatment because of its minimum trauma, less side effects, and so on. Photosen......

Cyclometalated iridium(III) complexes as mitochondria-targeted anticancer and antibacterial agents to induce both autophagy and apoptosis

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 219 ()

Mitochondrial damage will hinder the energy production of cells and produce excessive ROS (reactive oxygen species), resulting in cell death through a......

Enantiomeric selectivity of ruthenium (II) chiral complexes with antitumor activity, in vitro and in vivo

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 216 ()

Different enantiomers of chiral drugs show distinctive activities. Here, a pair of chiral ruthenium A-[Ru (phen)2(TPEPIP)]2+ (A-Ru), and A-[Ru(phen)2(......

Puerarin induces Nrf2 as a cytoprotective mechanism to prevent cadmium-induced autophagy inhibition and NLRP3 inflammasome activation in AML12 hepatic cells

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2021; 217 ()

Liver is the main target organ of cadmium (Cd) toxicity and puerarin (PU) has been shown to prevent Cd-induced hepatic cell damage via its antioxidant......

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