期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
DNA methylation is an important epigenetic mechanism that regulates gene expression. To date, most DNA methylation studies have focussed on CpG island......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background 5-Hydroxymethylcytosine (5hmC), an important DNA epigenetic modification, plays a vital role in tumorigenesis, progression and prognosis in......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background: DNA 5-hydroxymethylcytosine (5hmC) is produced by dynamic 5mC oxidation process contributing to tissue specification, and loss of 5hmC has......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
BackgroundStroke is the leading cause of mortality in China. DNA methylation has essential roles in multiple diseases, but its association with stroke......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background Noninvasive diagnostic markers that are capable of distinguishing patients with colorectal cancer (CRC) from healthy individuals or patient......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background Early detection of esophageal cancer is critical to improve survival. Whilst studies have identified biomarkers, their interpretation and v......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background SLC5A7 (solute carrier family 5 member 7), also known as choline transporter 1 (CHT1), is downregulated in colorectal cancer (CRC) and func......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
BackgroundWe screened out several hypermethylated solute carrier (SLC) family genes in acute myeloid leukemia by reduced representation bisulfite sequ......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Silicosis is one of the most severe occupational diseases worldwide and is characterized by silicon nodules and diffuse pulmonary fibrosis. However, s......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background: Fetal overgrowth programs an elevated risk of type 2 diabetes in adulthood. Epigenetic alterations may be a mechanism in programming the v......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Cryopreservation has important application in assisted reproductive technology (ART). The vitrification technique has been widely used in the cryopres......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Backgrounds Acute myocardial infarction (AMI) has been one of the most fatal diseases among all types of heart diseases due to its rapid onset and hig......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background: Aberrant epigenetic modifications such as DNA methylation may contribute to the pathogenesis of DR. We aimed at elucidating the role of no......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Most studies aiming to identify epigenetic biomarkers do so from complex tissues that are composed of many different cell-types. By definition, these ......
期刊： CLINICAL EPIGENETICS, 2022; 14 (1)
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a typical neurodegenerative disease......
