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Glioma-Derived TSP2 Promotes Excitatory Synapse Formation and Results in Hyperexcitability in the Peritumoral Cortex of Glioma

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021; 80 (2)

Seizures are common in patients with glioma, especially low-grade glioma (LGG). However, the epileptogenic mechanisms are poorly understood. Recent ev......

Downregulation of Long Noncoding RNA TUG1 Attenuates MTDH-Mediated Inflammatory Damage via Targeting miR-29b-1-5p After Spinal Cord Ischemia Reperfusion

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021; 80 (3)

Long noncoding RNAs and microRNAs (miRNAs) play a vital role in spinal cord ischemia reperfusion (IR) injury. The aim of this study was to identify th......

Neuroprotection of Heme Oxygenase-2 in Mice After Intracerebral Hemorrhage

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021; 80 (5)

There are few effective preventive or therapeutic strategies to mitigate the effects of catastrophic intracerebral hemorrhage (ICH) in humans. Heme ox......

Spatially Resolved and Quantitative Analysis of the Immunological Landscape in Human Meningiomas

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021; 80 (2)

The immunological status of human meningiomas is not well understood, hindering the development of rational immunotherapeutic strategies. We measured ......

The CTSC-RAB38 Fusion Transcript Is Associated With the Risk of Hemorrhage in Brain Arteriovenous Malformations

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021; 80 (1)

Brain arteriovenous malformations (bAVMs) are congenital anomalies of blood vessels that cause intracranial hemorrhage in children and young adults. C......

Silencing of lncRNA XLOC_035088 Protects Middle Cerebral Artery Occlusion-Induced Ischemic Stroke by Notch1 Signaling

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021; 80 (1)

Ischemic stroke represents one of the leading causes of mortality worldwide and especially in developing countries. It is crucial for finding effectiv......

Overexpression of Long Noncoding RNA HOTAIR Is a Unique Epigenetic Characteristic of Myxopapillary Ependymoma

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2020; 79 (11)

Ependymomas are a heterogeneous group of central nervous system tumors. Despite the recent advances, there are no specific biomarkers for ependymomas.......

PRKCA D463H Mutation in Chordoid Glioma of the Third Ventricle: A Cohort of 16 Cases, Including Two Cases Harboring BRAF(V600E) Mutation

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2020; 79 (11)

Chordoid gliomas (CG) of the third ventricle are characterized by chordoid and glial features, but the extent of histological variations across CG is ......

Fasciculation and Elongation Protein Zeta-1 Expression in Reactive Astrocytes in a Rat Model of Frontal Lobe Injury

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2020; 79 (2)

There are reports that depression induced by frontal lobe injury (FLI) has a devastating effect on human mental health. We previously reported that fa......

Gasdermine E-Dependent Mitochondrial Pyroptotic Pathway in Dermatomyositis: A Possible Mechanism of Perifascicular Atrophy

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2020; 79 (5)

Different mechanisms have been proposed to explain the pathological basis of perifascicular atrophy (PFA), a pathognomonic histologic feature of derma......

Integrative Transcriptome and Proteome Analyses Provide New Insights Into the Interaction Between Live Borrelia burgdorferi and Frontal Cortex Explants of the Rhesus Brain

期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2020; 79 (5)

Borrelia burgdorferi (Bb), which is neurotropic, can attack the central nervous system (CNS), leading to the development of various neurologic symptom......

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