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Extracellular signals regulate the biogenesis of extracellular vesicles

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of proteins and RNAs for intercellular communication. With ......

JIF:5.093

tiRNA-Val promotes angiogenesis via Sirt1-Hif-1 alpha axis in mice with diabetic retinopathy

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background: Diabetic retinopathy (DR) is a specific microvascular complication arising from diabetes, and its pathogenesis is not completely understoo......

JIF:5.093

Impact of inactivated SARS-CoV-2 vaccination on embryo ploidy: a retrospective cohort study of 133 PGT-A cycles in China

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Unsubstantiated concerns have been raised on the potential correlation between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)......

JIF:5.093

Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Betahistine is a clinical medication for the treatment of benign paroxysmal positional vertigo (BPPV). Otolin, a secreted glycoprotein with......

JIF:5.093

Structure and character analysis of cotton response regulator genes family reveals that GhRR7 responses to draught stress

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Cytokinin signal transduction is mediated by a two-component system (TCS). Two-component systems are utilized in plant responses to hormone......

JIF:5.093

Molecular structures and functional exploration of NDA family genes respond tolerant to alkaline stress in Gossypium hirsutum L.

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background The internal NAD(P)H dehydrogenase (NDA) gene family was a member of the NAD(P)H dehydrogenase (ND) gene family, mainly involved in the non......

JIF:5.093

Neuronal GRK2 regulates microglial activation and contributes to electroacupuncture analgesia on inflammatory pain in mice

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background G protein coupled receptor kinase 2 (GRK2) has been demonstrated to play a crucial role in the development of chronic pain. Acupuncture is ......

JIF:5.093

Intravitreal injection of mitochondrial DNA induces cell damage and retinal dysfunction in rats

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Retinal neurodegeneration is induced by a variety of environmental insults and stresses, but the exact mechanisms are unclear. In the prese......

JIF:5.093

Immature rat testis sustained long-term development using an integrative model

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Xenotransplantation has been primarily performed using fresh donor tissue to study testicular development for about 20 years, and whether t......

JIF:5.093

Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Metastatic melanoma has a high mortality rate and poor survival. This is associated with efficient metastatic colonization, but the underly......

JIF:5.093

Identification of 5-methylcytosine-related signature for predicting prognosis in ovarian cancer

期刊: BIOLOGICAL RESEARCH, 2021; 54 (1)

Background Ovarian cancer is one of the most common malignancies often resulting in a poor prognosis. 5-methylcytosine (m5C) is a common epigenetic mo......

The role of circular RNA circ_0008285 in gestational diabetes mellitus by regulating the biological functions of trophoblasts

期刊: BIOLOGICAL RESEARCH, 2021; 54 (1)

BackgroundCircular RNAs (circRNAs) has emerged as vital regulator involved in various diseases. In this study, we identified and investigated the pote......

Mvda is required for zebrafish early development

期刊: BIOLOGICAL RESEARCH, 2021; 54 (1)

Background The MVD gene mutations are identified in porokeratosis, which is considered a skin-specific autoinflammatory keratinization disease. Howeve......

Electroacupuncture suppresses glucose metabolism and GLUT-3 expression in medial prefrontal cortical in rats with neuropathic pain

期刊: BIOLOGICAL RESEARCH, 2021; 54 (1)

Background Accumulating evidence has demonstrated that the electroacupuncture (EA) stimulation could effectively alleviate neuropathic pain. The media......

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