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Induction of Differentiation of Mesenchymal Stem Cells into Retinal Pigment Epithelial Cells for Retinal Regeneration by Using Ciliary Neurotrophic Factor in Diabetic Rats

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (1)

Diabetic retinopathy (DR) is a common cause of blindness all over the world. Bone marrow mesenchymal stem cells (BMSCs) have been considered as a prom......

Fully Automatic Scar Segmentation for Late Gadolinium Enhancement MRI Images in Left Ventricle with Myocardial Infarction

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (2)

Numerous methods have been published to segment the infarct tissue in the left ventricle, most of them either need manual work, post-processing, or su......

Genetic Susceptibility Study of Chinese Sudden Sensorineural Hearing Loss Patients with Vertigo

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (4)

Objective To investigate the genetic causes of sudden sensorineural hearing loss (SSNHL) patients in China. This study focused on analyzing variations......

Characteristics of Viral Shedding in Respiratory Samples and Specific Antibodies Production in 564 COVID-19 Patients

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (1)

Positive nucleic acid (NA) results have been found in recovered and discharged COVID-19 patients, but the proportion is unclear. This study was design......

Clinical Features of Oxaliplatin-induced Hypersensitivity Reactions in Chinese Patients: A Retrospective Multicenter Analysis

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (4)

Objective The characteristics of oxaliplatin-induced hypersensitivity reactions (HSRs) in Chinese patients were investigated to provide a reference fo......

Influencing Factors for Erectile Dysfunction of Young Adults with No Response to PDE5i

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (3)

Erectile dysfunction (ED) is a common male disorder. Although orally-administered phosphodiesterase type 5 inhibitors (PDE5 inhibitors) are now recogn......

Prognostic Value of Feature-Tracking Circumferential Strain in Dilated Cardiomyopathy Patients with Severely Reduced Ejection Fraction Incremental to Late Gadolinium Enhancement

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (1)

Myocardial fiber deformation measurements have been reported to be associated with adverse outcomes in patients with acute heart failure and those wit......

BOP1 Silencing Suppresses Gastric Cancer Proliferation through p53 Modulation

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (2)

Block of proliferation 1 (BOP1) is a key protein involved in ribosome maturation and affects cancer progression. However, its role in gastric cancer (......

SOD2 Alleviates Hearing Loss Induced by Noise and Kanamycin in Mitochondrial DNA4834-deficient Rats by Regulating PI3K/MAPK Signaling

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (3)

Superoxide dismutase 2 (SOD2)-mediated gene therapy has significant protective effects against kanamycin-induced hearing loss and hair cell loss in th......

An Overview of Anterior Repositioning Splint Therapy for Disc Displacement-related Temporomandibular Disorders

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (3)

Anterior repositioning splint (ARS) therapy is considered one of the most effective therapies for treating disc displacement-related temporomandibular......

Downregulation of Cav3.1 T-type Calcium Channel Expression in Age-related Hearing Loss Model

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (4)

Objective Age-related hearing loss (AHL), characterized by degeneration of cochlea structures, is the most common sensory disorder among the elderly w......

Knockdown of Microtubule Associated Serine/threonine Kinase Like Expression Inhibits Gastric Cancer Cell Growth and Induces Apoptosis by Activation of ERK1/2 and Inactivation of NF-kappa B Signaling

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (1)

Microtubule-associated serine/threonine kinase (MASTL) functions to regulate chromosome condensation and mitotic progression. Therefore, aberrant MAST......

Losartan Protects Podocytes against High Glucose-induced Injury by Inhibiting B7-1 Expression

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (3)

The role of B7-1 in podocyte injury has received increasing attention. The aim of this study was to investigate whether losartan protects podocytes of......

The Potential Immunomodulatory Properties of Levornidazole Contribute to Improvement in Experimental Ulcerative Colitis

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (4)

The use of an antibiotic with immunomodulatory properties could be fascinating in treating multifactorial inflammatory conditions such as ulcerative c......

Migraine and Cochlear Symptoms

期刊: CURRENT MEDICAL SCIENCE, 2021; 41 (4)

Migraine is one of the most common and highest burdens of disease. As a primary cerebral dysfunction illness, migraine might exhibit other system-rela......

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