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Fitness benefits play a vital role in the retention of the Pi-ta susceptible alleles

期刊: GENETICS, 2022; 220 (4)

In plants, large numbers of R genes, which segregate as loci with alternative alleles conferring different levels of disease resistance to pathogens, ......

JIF:4.252

Olfactory receptor subgenome and expression in a highly olfactory procellariiform seabird

期刊: GENETICS, 2022; 220 (2)

Procellariiform seabirds rely on their sense of smell for foraging and homing. Both genomes and transcriptomes yield important clues about how olfacto......

JIF:4.252

Statistical analysis of spatially resolved transcriptomic data by incorporating multiomics auxiliary information

期刊: GENETICS, 2022; 221 (4)

Effective control of false discovery rate is key for multiplicity problems. Here, we consider incorporating informative covariates from external datas......

JIF:4.252

Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin

期刊: GENETICS, 2022; 220 (1)

Aspergillus fumigatus is the main causative agent of invasive pulmonary aspergillosis (IPA), a severe disease that affects immunosuppressed patients w......

JIF:4.252

LKB1 is physiologically required for sleep from Drosophila melanogaster to the Mus musculus

期刊: GENETICS, 2022; 221 (3)

Liver Kinase B1 (LKB1) is known as a master kinase for 14 kinases related to the adenosine monophosphate-activated protein kinase. Two of them salt in......

JIF:4.252

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-beta pathway in Drosophila

期刊: GENETICS, 2022; 220 (3)

Inflammaging refers to low-grade, chronically activated innate immunity that has deleterious effects on healthy lifespan. However, little is known abo......

JIF:4.252

Roles of anti-Mullerian hormone and its duplicates in sex determination and germ cell proliferation of Nile tilapia

期刊: GENETICS, 2022; 220 (3)

Duplicates of amh are crucial for fish sex determination and differentiation. In Nile tilapia, unlike in other teleosts, amh is located on X chromosom......

JIF:4.252

Network regression analysis for binary and ordinal categorical phenotypes in transcriptome-wide association studies

期刊: GENETICS, 2022; 222 (4)

Transcriptome-wide association studies aim to integrate genome-wide association studies and expression quantitative trait loci mapping studies for exp......

JIF:4.252

Presynaptic G alpha(o) (GOA-1) signals to depress command neuron excitability and allow stretch-dependent modulation of egg laying in Caenorhabditis elegans

期刊: GENETICS, 2021; 218 (4)

Egg laying in the nematode worm Caenorhabditis elegans is a two-state behavior modulated by internal and external sensory input. We have previously sh......

Repeated horizontal gene transfer of GALactose metabolism genes violates Dollo's law of irreversible loss

期刊: GENETICS, 2021; 217 (2)

Dollo's law posits that evolutionary losses are irreversible, thereby narrowing the potential paths of evolutionary change. While phenotypic reversals......

Cotton Fiber Development Requires the Pentatricopeptide Repeat Protein GhIm for Splicing of Mitochondrial nad7 mRNA

期刊: GENETICS, 2021; 217 (1)

Pentatricopeptide repeat (PPR) proteins encoded by nuclear genomes can bind to organellar RNA and are involved in the regulation of RNA metabolism. Ho......

Dri1 mediates heterochromatin assembly via RNAi and histone deacetylation

期刊: GENETICS, 2021; 218 (1)

Heterochromatin, a transcriptionally silenced chromatin domain, is important for genome stability and gene expression. Histone 3 lysine 9 methylation ......

Modulation of the complex regulatory network for methionine biosynthesis in fungi

期刊: GENETICS, 2021; 217 (2)

The assimilation of inorganic sulfate and the synthesis of the sulfur-containing amino acids methionine and cysteine is mediated by a multibranched bi......

Caenorhabditis elegans junctophilin has tissue-specific functions and regulates neurotransmission with extended-synaptotagmin

期刊: GENETICS, 2021; 218 (4)

The junctophilin family of proteins tether together plasma membrane (PM) and endoplasmic reticulum (ER) membranes, and couple PM-and ER-localized calc......

The fitness costs and benefits of trisomy of each Candida albicans chromosome

期刊: GENETICS, 2021; 218 (2)

Candida albicans is a prevalent human fungal pathogen. Rapid genomic change, due to aneuploidy, is a common mechanism that facilitates survival from m......

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