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Long noncoding RNA#45 exerts broad inhibitory effect on influenza a virus replication via its stem ring arms

期刊: VIRULENCE, 2021; 12 (1)

A growing body of evidence suggests the pivotal role of long non-coding RNA (lncRNA) in influenza virus infection. Based on next-generation sequencing......

Colibactin in avian pathogenic Escherichia coli contributes to the development of meningitis in a mouse model

期刊: VIRULENCE, 2021; 12 (1)

Colibactin is synthesized by a 54-kb genomic island, leads to toxicity in eukaryotic cells, and plays a vital role in many diseases, including neonata......

Insights of roles played by septins in pathogenic fungi

期刊: VIRULENCE, 2021; 12 (1)

Septins, a conserved family of GTP-binding proteins, are widely recognized as an essential cytoskeletal component, playing important roles in a variet......

Complement receptor 3 mediates Aspergillus fumigatus internalization into alveolar epithelial cells with the increase of intracellular phosphatidic acid by activating FAK

期刊: VIRULENCE, 2021; 12 (1)

Complement receptor 3 (CD11b/CD18) is an important receptor that mediates adhesion, phagocytosis and chemotaxis in various immunocytes. The conidia of......

Time-dependent viral interference between influenza virus and coronavirus in the infection of differentiated porcine airway epithelial cells

期刊: VIRULENCE, 2021; 12 (1)

Coronaviruses and influenza viruses are circulating in humans and animals all over the world. Co-infection with these two viruses may aggravate clinic......

Glycosylation on envelope glycoprotein of duck Tembusu virus affects virus replication in vitro and contributes to the neurovirulence and pathogenicity in vivo

期刊: VIRULENCE, 2021; 12 (1)

Duck Tembusu virus (DTMUV), an emergent flavivirus, causes domestic waterfowls to suffer from severe egg-drop syndrome and fatal encephalitis, greatly......

Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration

期刊: VIRULENCE, 2021; 12 (1)

Airway epithelial cells are the first line of defense against respiratory pathogens. Porcine bacterial pathogens, such as Bordetella bronchiseptica, A......

The tyrosine phosphatase SHP-2 dephosphorylated by ALV-J via its Env efficiently promotes ALV-J replication

期刊: VIRULENCE, 2021; 12 (1)

Avian leukosis virus subgroup J (ALV-J) generally induces hemangioma, myeloid leukosis, and immunosuppression in chickens, causing significant poultry......

The biological role of MutT in the pathogenesis of the zoonotic pathogen Streptococcus suis serotype 2

期刊: VIRULENCE, 2021; 12 (1)

Streptococcus suis (S. suis) is an important rising pathogen that causes serious diseases in humans and pigs. Although some putative virulence factors......

Staphylococcus aureus N-terminus formylated delta-toxin tends to form amyloid fibrils, while the deformylated delta-toxin tends to form functional oligomer complexes

期刊: VIRULENCE, 2021; 12 (1)

The community-associated Methicillin-resistant Staphylococcus aureus strain (CA-MRSA) is highly virulent and has become a major focus of public health......

Genetic diversity and evolution of the virulence plasmids encoding aerobactin and salmochelin in Klebsiella pneumoniae

期刊: VIRULENCE, 2021; 12 (1)

Virulence plasmids of hypervirulent Klebsiella pneumoniae (hvKp) have the potential to transfer to drug-resistant strains or integrate with other plas......

Genomic population structure of Helicobacter pylori Shanghai isolates and identification of genomic features uniquely linked with pathogenicity

期刊: VIRULENCE, 2021; 12 (1)

Severe Helicobacter pylori-linked gastric disorders are especially prevalent in the East Asia region. The ability of H. pylori to cause different clin......

A biological and genomic comparison of a drug-resistant and a drug-susceptible strain of Candida auris isolated from Beijing, China

期刊: VIRULENCE, 2021; 12 (1)

The fungal pathogen Candida auris has emerged as a new threat to human health. We previously reported the first isolate of C. auris (BJCA001) in China......

Diversification and prevalence of the quinolone resistance crpP genes and the crpP-carrying Tn6786-related integrative and conjugative elements in Pseudomonas aeruginosa

期刊: VIRULENCE, 2021; 12 (1)

The quinolone resistance crpP genes can mediate decreased susceptibility to quinolones. However, diversification and prevalence of crpP genes and crpP......

Functional analysis of seven regulators of G protein signaling (RGSs) in the nematode-trapping fungus Arthrobotrys oligospora

期刊: VIRULENCE, 2021; 12 (1)

Regulators of G protein signaling (RGSs) are proteins that negatively regulate G protein signal transduction. In this study, seven putative RGSs were ......

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