期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Tumor infiltrating mast cells (TIMs), with pro- or anti-tumorigenic role in different types of malignancies, have been implicated in resistance to ant......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
The success of checkpoint immunotherapy has created optimism that cancer may be curable. However, not all patients respond, resistance is common and m......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Although PD-1/PD-L1 blockade therapy confers salutary effects across cancer types, their efficacy in Extranodal Natural killer/T-cell lymphoma (ENKTCL......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
PD-L2 expression is an important predictor of anti-PD-1 therapy efficacy in patients with head and neck squamous cell carcinoma (HNSCC). However, whet......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Alternol is a naturally occurring compound that exerts antitumor activity in several cancers. However, whether Alternol induces antitumor immune respo......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Although all murine MDSCs are defined as Gr1(+)CD11b(+), their true immunophenotype remains elusive. In this study, we found murine Gr1(+)CD11b(+) cel......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Malignant cells adapt to the hostile tumor microenvironment by escaping from, or actively suppressing, anticancer immune responses. In the past, we re......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Glioblastoma (GBM) is the most common and aggressive brain malignancy in adults and is currently incurable with conventional therapies. The use of chi......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Background The present study aimed to evaluate the effects of concomitant proton pump inhibitor (PPI) use on immune checkpoint inhibitor (ICI) efficac......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Immunotherapy that block PD-1-PD-L1 pathway can induce durable tumor control and result in the long-term survival of patients with advanced bladder ca......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Immunotherapy shows promising therapeutic efficacy against various types of cancer, but most fail to respond. Preclinical studies have suggested that ......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Metastasis and immune suppression account for the poor prognosis of oral squamous cell carcinoma (OSCC). YKT6 is a member of the soluble NSF attachmen......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Although the vast majority of patients with papillary thyroid cancer (PTC) have a favorable prognosis when conventional treatments are implemented, lo......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Interferons (IFNs) are a large family of pleiotropic cytokines that regulate both innate and adaptive immunity and show anti-cancer effects in various......
期刊: ONCOIMMUNOLOGY, 2021; 10 (1)
Clear cell renal cell carcinoma (ccRCC) is the most common kidney malignancy characterized by a poor prognosis. The treatment efficacy of immune check......