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MiR-4763-3p targeting RASD2 as a Potential Biomarker and Therapeutic Target for Schizophrenia

期刊: AGING AND DISEASE, 2022; 13 (4)

Existing diagnostic methods are limited to observing appearance and demeanor, even though genetic factors play important roles in the pathology of sch......

JIF:6.503

Association between Parkinson's Disease and Diabetes Mellitus: From Epidemiology, Pathophysiology and Prevention to Treatment

期刊: AGING AND DISEASE, 2022; 13 (6)

Diabetes mellitus (DM) and Parkinson's disease (PD) are both age-related diseases of global concern being among the most common chronic metabolic and ......

JIF:6.503

Sarcopenic Obesity: An Emerging Public Health Problem

期刊: AGING AND DISEASE, 2022; 13 (2)

Population aging and the obesity epidemic are important global public health problems that pose an unprecedented threat to the physical and mental hea......

JIF:6.503

Potential Effect of the Circadian Clock on Erectile Dysfunction

期刊: AGING AND DISEASE, 2022; 13 (1)

The circadian rhythm is an internal timing system, which is generated by circadian clock genes. Because the circadian rhythm regulates numerous cellul......

JIF:6.503

ACE2 and COVID-19 Susceptibility and Severity

期刊: AGING AND DISEASE, 2022; 13 (2)

Sick, male, and older populations are more vulnerable to COVID-19. However, it remains unclear whether a common mechanism exists across different demo......

JIF:6.503

Aquaporin-4 and Cognitive Disorders

期刊: AGING AND DISEASE, 2022; 13 (1)

Aquaporin-4 (AQP4) is the most abundantly expressed aquaporin in the central nervous system (CNS) and is an integral part of the glymphatic system tha......

JIF:6.503

The Functional Role of Lipoproteins in Atherosclerosis: Novel Directions for Diagnosis and Targeting Therapy

期刊: AGING AND DISEASE, 2022; 13 (2)

Dyslipidemia, characterized by a high level of lipids (cholesterol, triglycerides, or both), can increase the risk of developing and progressing ather......

JIF:6.503

Cellular Senescence in Cardiovascular Diseases: A Systematic Review

期刊: AGING AND DISEASE, 2022; 13 (1)

Aging is a prominent risk factor for cardiovascular diseases, which is the leading cause of death around the world. Recently, cellular senescence has ......

JIF:6.503

EP3 Receptor Deficiency Improves Vascular Remodeling and Cognitive Impairment in Cerebral Small Vessel Disease

期刊: AGING AND DISEASE, 2022; 13 (1)

Aging and hypertension are major risk factors for cerebral small vessel disease (CSVD). Anti hypertensive therapy has achieved effective; however, inc......

JIF:6.503

Emerging Roles of Ceramide in Cardiovascular Diseases

期刊: AGING AND DISEASE, 2022; 13 (1)

Ceramide is a core molecule of sphingolipid metabolism that causes selective insulin resistance and dyslipidemia. Research on its involvement in cardi......

JIF:6.503

CB2R Attenuates Intervertebral Disc Degeneration by Delaying Nucleus Pulposus Cell Senescence through AMPK/GSK3 beta Pathway

期刊: AGING AND DISEASE, 2022; 13 (2)

Nucleus pulposus (NP) cell (NPC) senescence is one of the main causes of inters ertebral disc degeneration (IVDD). However, the underlying mechanism o......

JIF:6.503

Ongoing Clinical Trials in Aging-Related Tissue Fibrosis and New Findings Related to AhR Pathways

期刊: AGING AND DISEASE, 2022; 13 (2)

Fibrosis is a pathological manifestation of wound healing that replaces dead/damaged tissue with collagen-rich scar tissue to maintain homeostasis, an......

JIF:6.503

Impact of CircRNAs on Ischemic Stroke

期刊: AGING AND DISEASE, 2022; 13 (2)

Circular RNA (circRNA) is a recently discovered class of endogenous non-coding RNA that is generated by cyclization, driven by intron pairing, and reg......

JIF:6.503

Intrinsic Capacity in Older Adults: Recent Advances

期刊: AGING AND DISEASE, 2022; 13 (2)

The global increase in the aging population is expected to result in a shift from disease-centered to function-centered approaches in response to inte......

JIF:6.503

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