The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial

Loomba, R; Lawitz, E; Mantry, PS; Jayakumar, S; Caldwell, SH; Arnold, H; Diehl, AM; Djedjos, CS; Han, L; Myers, RP; Subramanian, GM; McHutchison, JG; Goodman, ZD; Afdhal, NH; Charlton, MR

Loomba, R (reprint author), Univ Calif San Diego, Div Gastroenterol & Epidemiol, NAFLD Res Ctr, 9500 Gilman Dr,MC 0887, La Jolla, CA 92093 USA.

HEPATOLOGY, 2018; 67 (2): 549

Abstract

Inhibition of apoptosis signal-regulating kinase 1, a serine/threonine kinase, leads to improvement in inflammation and fibrosis in animal models of n......

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