Anti-glypican-1 antibody-drug conjugate exhibits potent preclinical antitumor activity against glypican-1 positive uterine cervical cancer

Matsuzaki, S; Serada, S; Hiramatsu, K; Nojima, S; Matsuzaki, S; Ueda, Y; Ohkawara, T; Mabuchi, S; Fujimoto, M; Morii, E; Yoshino, K; Kimura, T; Naka, T

Yoshino, K (reprint author), Osaka Univ, Grad Sch Med, Dept Obstet & Gynecol, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan.; Serada, S (reprint author), Kochi Univ, Ctr Intractable Immune Dis, Kochi Med Sch, Nankoku, Kochi 7838505, Japan.

INTERNATIONAL JOURNAL OF CANCER, 2018; 142 (5): 1056

Abstract

Glypican-1 (GPC1) is highly expressed in solid tumors, especially squamous cell carcinomas (SCCs), and is thought to be associated with disease progre......

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