Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome

Tosar, JP; Segovia, M; Castellano, M; Gambaro, F; Akiyama, Y; Fagundez, P; Olivera, A; Costa, B; Possi, T; Hill, M; Ivanov, P; Cayota, A

Tosar, JP (corresponding author), Univ Republica, Fac Sci, Nucl Res Ctr, Analyt Biochem Unit, Montevideo, Uruguay.; Tosar, JP; Cayota, A (corresponding author), Inst Pasteur Montevideo, Funct Genom Unit, Montevideo, Uruguay.; Tosar, JP (corresponding author), Brigham & Womens Hosp, Div Rheumatol Immunol & Allergy, 75 Francis St, Boston, MA 02115 USA.; Tosar, JP (corresponding author), Harvard Med Sch, Dept Med, Boston, MA 02115 USA.; Cayota, A (corresponding author), Univ Republica, Univ Hosp, Dept Med, Montevideo, Uruguay.

NUCLEIC ACIDS RESEARCH, 2020; 48 (22): 12874

Abstract

A major proportion of extracellular RNAs (exRNAs) do not copurify with extracellular vesicles (EVs) and remain in ultracentrifugation supernatants of ......

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