The circadian E3 ligase complex SCFFBXL3+CRY targets TLK2

Correia, SP; Chan, AB; Vaughan, M; Zolboot, N; Perea, V; Huber, AL; Kriebs, A; Moresco, JJ; Yates, JR; Lamia, KA

Lamia, KA (reprint author), Scripps Res Inst, Dept Mol Med, 10550 North Torrey Pines Rd, La Jolla, CA 92037 USA.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

We recently demonstrated that the circadian clock component CRY2 is an essential cofactor in the SCFFBXL3-mediated ubiquitination of c-MYC. Because ou......

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