Inhibition of Mammalian Target of Rapamycin Signaling with Rapamycin Prevents Trauma-Induced Heterotopic Ossification

Qureshi, AT; Dey, D; Sanders, EM; Seavey, JG; Tomasino, AM; Moss, K; Wheatley, B; Cholok, D; Loder, S; Lit, J; Levi, B; Davis, TA

Davis, TA (reprint author), Uniformed Serv Univ Hlth Sci, Dept Surg, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA.; Davis, TA (reprint author), Walter Reed Natl Mil Med Ctr, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA.

AMERICAN JOURNAL OF PATHOLOGY, 2017; 187 (11): 2536

Abstract

A pressing clinical need exists for 63% to 65% of combat-wounded service members and 11% to 20% of civilians who develop heterotopic ossification (HO)......

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