Nitidine Chloride-Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism

Mao, X; Wang, J; Wang, Q; Yang, L; Li, YL; Lin, H; Peng, Y; Zheng, J

Peng, Y; Zheng, J (reprint author), Shenyang Pharmaceut Univ, Wuya Coll Innovat, Shenyang 110016, Liaoning, Peoples R China.; Zheng, J (reprint author), Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Key Lab Pharmaceut Guizhou Prov, Guiyang

DRUG METABOLISM AND DISPOSITION, 2019; 47 (8): 919

Abstract

The cytochrome P450 (P450) 1 family is an important phase I enzyme involved in carcinogen activation. Nitidine chloride (NC) is a pharmacologically ac......

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