A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy

Zhou, ZA; Feng, ZW; Hu, D; Yang, P; Gur, M; Bahar, I; Cristofanilli, M; Gradishar, WJ; Xie, XQ; Wan, Y

Wan, Y (reprint author), Northwestern Univ, Feinberg Sch Med, Dept Obstet & Gynecol, Chicago, IL 60611 USA.; Wan, Y (reprint author), Robert H Lurie Comprehens Canc Ctr, Lurie Med Res Ctr, 303 East Super, Chicago, IL 60611 USA.; Xie, XQ (reprint author),

EBIOMEDICINE, 2019; 44 (): 98

Abstract

Background: Triple negative breast cancers (TNBCs) have a poor prognosis and are not amenable to endocrine- or HER2-targeted therapies. The malignant ......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索