The therapeutic potential of targeting CD73 and CD73-derived adenosine in melanoma

Soleimani, A; Farshchi, HK; Mirzavi, F; Zamani, P; Ghaderi, A; Amini, Y; Khorrami, S; Mashayekhi, K; Jaafari, MR

Jaafari, MR (corresponding author), Mashhad Univ Med Sci, Sch Pharm, Dept Pharmaceut Nanotechnol, Mashhad, Razavi Khorasan, Iran.

BIOCHIMIE, 2020; 176 (): 21

Abstract

The hypoxic environment of melanoma results in CD73 upregulation on the surface of various tumor microenvironment (TME) cells including tumor cells, s......

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