SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity

Yue, T; Zhan, XM; Zhang, DW; Jain, RC; Wang, KW; Choi, JH; Misawa, T; Su, LJ; Quan, JX; Hildebrand, S; Xu, DR; Li, XH; Turer, E; Sun, L; Moresco, EMY; Beutler, B

Beutler, B (corresponding author), Univ Texas Southwestern Med Ctr, Ctr Genet Host Def, Dallas, TX 75390 USA.

SCIENCE, 2021; 372 (6543): 703

Abstract

Reactive oxygen species (ROS) increase in activated T cells because of metabolic activity induced to support T cell proliferation and differentiation.......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索